COVID-19 Pneumonia
Conditions
Brief summary
COVID-19 clotting Safety
Detailed description
Covid-19 patients have liability for hyper coagulability, low level laser Therapy improve circulation and decrease liability for hyper coagulability accompanied with circulatory exercises .
Interventions
RADIATIONLow level laser Therapy
Pin pointed application of low level laser on 15 acupuncture points each point 1 min time of application 15 min.
OTHERCirculatory exercises
Active assisted or against mild resistance. Supine with leg up position 18degrees measured by the bed water balance in side rails. If patient is not comfortable according to the modified Borg scale or contra indicated for the position then assume the supine position. The subject will have A 3 min rest period to acclimatize themselves to each position. The ankle pumping exercises consisted of simple repetitions of dorsiflexion 1 sec and planter- flexion for 1 sec with three different exercise intervals: * repeated dorsiflexion and planter-flexion with no rest (no rest exercise). * repeated dorsiflexion and planter-flexion with a 2 sec rest period (2 sec rest exercise). * repeated dorsiflexion and planter-flexion with 4sec rest period (4sec rest exercise). Subjects will have practiced ankle pumps before the exercise to get familiar and be educated about the procedure.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Caregiver)
Masking description
circulatory exercise only, circulatory exercises and LLLT.
Intervention model description
Two groups of 30 patients, 1st circulatory exercise, 2nd LLLT and circulatory exercises.
Eligibility
Sex/Gender
ALL
Age
35 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI from 18.5 to 29.9 kg/m2 * Moderate elevated percentage of coagulative factors for COVID-19 Diagnosis: * Nasopharyngeal swab * Sepsis induced coagulopathy score\>4 * D\_dimer≥0,5mg/L * Fibrinogen\>2,5gm/L * C\_reactive protein≥10mg/L * Lymphocyte count\<1,500mm3 * Platelet count\<150,000mm3 * Prothrombin time increase\>3sec * Activated partial thromboplastin time increase\>5sec * Same level of physical activity * Patients can swallow tablets * CT scan screening method for COVID-19 Diagnosis * Physical examination
Exclusion criteria
* hyper tension * Cognitive impairment e.g (delirium) * Diabetes mellitus both types dependant or non * Disabled musculoskeletal Disorders e.g hemi paresis * Coronary artery diseases and heart failure * DVT * Stroke, bone disease, renal failure, pulmonary embolism * Vitamins deficiency * 6 months post large surgeries * Alcohol intake and smokers * Thyroid diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Especially Lab investigation. | Baseline | C-reactive protein ≥10mg/l for diagnosis of the recovery. |
| Circulatory group laboratory investigation. | Monthly (an average of two months) | D-dimer≥.5mg/dL, fibrinogen\>2.5mg/dL To examine COVID-19 recovery. |
| Circulatory group: CBC analysis. | Daily (an average of two months) | Lymphocyte count\<1.500mm3, Platelet count\<150.000mm3, to examine COVID-19 recovery. |
| Circulatory group (PT, PTT). | Bi weekly (an average of two months) | Prothrombin time\>3 sec, activated partial thromboplastin time\>5 sec to examine COVID-19 recovery. |
| Circulatory group physical examination. | Every two days (an average of two months) | by visual analog scale is horizontal line 100mm length the ends defined as extreme limit of the parameter measured (symptom, pain, health) orientated from the left (the worst) the right (the best) 3 times per week to detect DVT. |
| Circulatory group. BMI. | Day one | weight kg on height m2 to detect liability for DVT. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| LLLT group laboratory investigation. | Monthly (an average of two months) | D-dimer≥,5mg/dl, fibrinogen\>2.5mg/dl, c-reactive protein≥10mg/dl to examine COVID-19 recovery. Fibrinogen |
| LLLT group CBC analysis. | Daily (an average of two months) | lymphocyte count\<1,500mm3, platelet count\<150,000mm3, for examine COVID-19 recovery. |
| LLLT group. {PTT, PT}. | Bi weekly (an average of two months) | Prothrombin time\>3 sec, activated partial thromboplastin time\>5sec to examine COVID-19 recovery. |
| LLLT group physical examination. | Every two days (an average of two months) | by visual analog scale is a straight horizontal line of fixed length 100mm the end is extreme limit of the parameter measured (symptom, pain, health) orientated from the left (the worst) to the right (the best) 3times per week to detect DVT. |
| LLLT group. BMI. | Day one | Weight kg/height m2 to detect liability for DVT. |
| Specifically Lab investigation. | Baseline | C\_reactive protein≥10mg/l.help diagnosis of the recovery. |
Countries
Egypt
Contacts
Primary ContactEnas Dr Ahmed, BSC
Outcome results
None listed