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The Effect of Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction With and Without Suture Tape Reinforcement

The Effect of Accelerated Rehabilitation After Anterior Cruciate Ligament Reconstruction With and Without Suture Tape Reinforcement

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05270551
Enrollment
114
Registered
2022-03-08
Start date
2026-05-01
Completion date
2027-05-01
Last updated
2026-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACL Injury

Keywords

Rehabilitation

Brief summary

The aim of our study is to evaluate the effect of accelerated rehabilitation post ACL reconstruction with and without augmentation on graft healing and return to normal activity clinically by scoring system and radiologically.

Detailed description

ACL reconstruction is the most commonly performed knee ligament reconstruction and employs a variety of surgical techniques. However, despite high success rates, it is still challenged by residual laxity and graft rupture. While the majority of patients who undergo ACLR will have good to excellent results, a subset of patients is at a higher risk for graft failure. For those that require revision surgery, the second operation often fails. Anterior cruciate ligament injuries account for 50% of knee ligament injuries for high school-aged adults. The most commonly used autografts for ACLR are the hamstring tendons (HT) and the bone-patellar tendon-bone (BPTB). However, questions remain about how patients with either an HT or a BPTB autograft recover knee muscle strength postoperatively. To help address and prevent future ACL failures, new repair and reconstruction techniques have been employed that incorporate suture augmentation. The goal of augmentation is to protect the newly repaired or reconstructed ligament during rehabilitation. Despite advances in anterior cruciate ligament (ACL) reconstruction surgical techniques and rehabilitation, recent studies report that between 20% to 50% of those with ACL reconstruction do not return to the same sports after surgery and 10% to 70% of those who resume preinjury sports participate at a reduced level or with significant functional impairments. Anecdotal evidence from patient report and clinical observation suggests that an inability to return to sports after ACL reconstruction can be partially attributed to a fear of reinjuring the knee.

Interventions

PROCEDUREACL Reconstruction

All participants will do ACL reconstruction with and without Augmentation and will receive Accelerated rehabilitation program

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
15 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Age from 15 to 50 years old. * With or without meniscal injury. * Isolated ACL injury without any other ligament injury. * Recent and chronic injury.

Exclusion criteria

* Multiligament injury. * Deformed knee (Genu varus or valgus). * Previous ACL reconstruction or repair. * Older than 50 years old and younger than 15 years old. * Failed ACL reconstruction or repair -

Design outcomes

Primary

MeasureTime frameDescription
Clinical outcome1 year follow upTegner Lysholm scores, which assesses activity levels

Secondary

MeasureTime frameDescription
Radiological outcome6 months follow upMagnetic resonance imaging (MRI) to assess graft healing, ACL tear and graft loosening

Contacts

CONTACTMohamed Abdel Tawab, Master
mohamedtawab8892@gmail.com+201022141998
STUDY_CHAIRMohamed Abdel Hamid, Professor

Mohamad Mohamed Abdel-Hamid Morsy

PRINCIPAL_INVESTIGATORHatem Galal El-Din Zaki, Professor

Hatem Galal El-Din Zaki

STUDY_DIRECTORMohamed Abd El-Radi, Lecturer

Mohamed Abd El-Radi Abd El-Salam

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 1, 2026