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Effects of Brachial Plexus Block on Tissue Oxygenation

Effects of Brachial Plexus Block Applied With Different Approaches on Tissue Oxygenation

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05269251
Acronym
BrachialPlexus
Enrollment
99
Registered
2022-03-07
Start date
2021-04-12
Completion date
2022-08-01
Last updated
2024-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tissue Oxygenation

Brief summary

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Detailed description

It has been reported that vasodilation after peripheral nerve blocks increases tissue oxygenation and increases arterial circulation on the ipsilateral side . Near Infrared Spectroscopy (NIRS), a noninvasive measurement method of tissue oxygen level, is used to measure regional hemoglobin oxygen saturation of arterial, venous and capillary blood . Many studies have compared the effects of upper extremity peripheral nerve blocks on the onset, quality, extent, and postoperative pain of sensory and motor block through axillary, infraclavicular, supraclavicular and interscalene approaches. The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Interventions

After the brachial plexus block, the regional oxygen saturation (rSO2) was monitored for 30 minutes with the Regional Oximetry System (O3™, Masimo, Irvine, CA) and the radial artery diameter with ultrasound in the same period.

Sponsors

Gazi University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* ASA I-III patients * Patients between the ages of 18 and 65 * Patients who applied axillary block * Patients who applied infraclavicular block * Patients who applied interscalene block

Exclusion criteria

* Peripheral nerve disease a history * History of thrombosis in the extremity to be blocked * History of embolism in the extremity to be blocked * Presence of neuropathy

Design outcomes

Primary

MeasureTime frameDescription
tissue oxygenation30 minutesMeasured from both extremities by Near Infrared Spectroscopy for 30 min after brachial nerve block.

Secondary

MeasureTime frameDescription
Radial artery diameter30 minutesmeasured on the side of the block after brachial nerve block

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026