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Adductor Canal Block Combined With IPACK vs Genicular Nerves Block in Knee Arthroscopy

Analgesic Effect of Adductor Canal Block Combined With Infiltration of the Interspace Between Popliteal Artery and the Capsule of the Knee (IPACK) Block Versus Genicular Nerves Block in Knee Arthroscopy

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05269095
Enrollment
105
Registered
2022-03-07
Start date
2022-03-21
Completion date
2023-03-21
Last updated
2022-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthroscopy, Genicular Nerves Block

Brief summary

This prospective randomized controlled study is designed to investigate the postoperative analgesic effect of adductor canal block (ACB) combined with infiltration of the interspace between the popliteal artery and the capsule of posterior knee (IPACK) block compared to genicular nerves block in patients undergoing knee arthroscopy.

Detailed description

Maintaining patient safety, ensuring best patient outcomes, and optimal pain relief post-operatively are of utmost concern for anesthesia providers. Adequate pain relief attenuates stress responses and long-term chronic pain complications while contributing to improved postoperative outcomes. Knee arthroscopy is a very common procedure and very often is performed as day-case surgery. Ambulatory arthroscopic surgery of the knee is preferred by the majority of properly selected and well-informed patients. It has been reported that a significant number of patients have moderate to severe pain 24 hours after ambulatory surgery in general and knee arthroscopy in particular and pain affects the patient's activity level and satisfaction. Adductor canal block (ACB) is a popular peripheral nerve block that has been shown to decrease the pain significantly and decrease opioid consumption with minimal effect on quadriceps function. It provides analgesia to the peri-articular and intra-articular aspects of the knee joint but doesn't relieve posterior knee pain which is moderate to severe in intensity.

Interventions

PROCEDURESpinal anesthesia only

Patients will receive spinal anesthesia with 2-3 ml 0.5% (10-15 mg) hyperbaric bupivacaine plus 25 ug fentanyl at the L3/4 interspaces.

BIOLOGICALSpinal anesthesia and ultrasound-guided Genicular nerves block

Patients will receive16 ml bupivacaine 0025% will be administered, and4 ml of this solution will be placed at each of the 4 target nerves.

BIOLOGICALUltrasound-guided Adductor Canal block (ACB) technique with infiltration of the interspace between popliteal artery and the capsule of posterior knee block ('PACK)

Adductor Canal block (ACB) technique will be performed using 16 ml bupivacaine 0025% As regarding the Popliteal artery and the capsule of posterior knee block ('PACK), it will be performed Using 16 ml bupivacaine 0.25%

Sponsors

Tanta University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
21 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Age 21-60 years * Both genders * American Society of Anaesthesiologists physical status classification I - III * Patients scheduled for elective unilateral knee arthroscopy under spinal anesthesia

Exclusion criteria

* Patient refusal * Preoperative neurological deficits * Opioid-dependent (opioid intake more than 3 months) * Chronic pain conditions * Significant cardiac and respiratory disease * Pre-existing major organ dysfunction such as hepatic and renal failure * Coexisting hematological disorder or deranged coagulation parameters * Psychiatric illnesses * Allergy to any of the drugs used in the study

Design outcomes

Primary

MeasureTime frameDescription
Postoperative 24-hour rescue analgesic consumption24 hours postoperativeTotal postoperative 24-hour rescue analgesic consumption will be recorded

Secondary

MeasureTime frameDescription
Post-operative pain24 hours PostoperativePost-operative pain will be assessed by the Numeric Rating Scale (NRS) rest and mobilization.
Time taken till 1st rescue analgesic request24 hours PostoperativeThe time till administration of first rescue analgesia will be recorded

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026