Revascularisation of Autotransplanted Teeth

Revascularisation of Autotransplanted Teeth - Retrospective Analysis of a Novel Technique

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05267249

Enrollment

Registered

2022-03-04

Start date

2021-08-06

Completion date

2022-02-15

Last updated

2026-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endodontic Disease, Pulp Canal Obliteration

Keywords

Autotransplantation, Apicoectomy, Revascularisation

Brief summary

Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection Note: The study was registered on Clinicaltrials.gov after termination of study.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

12 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Male and female consenting and judicious young people and adults * Written consent of the participant and, if applicable, of the legal guardian after education * Planned tooth transplantation with advanced or completed root growth

Exclusion criteria

* Contraindications for magnetic resonance imaging (MRI): (pronounced metal restorations, running orthodontics with metal, fixed appliance in the target jaw) * Current or past antiresorptive therapy with bisphosphonates * Further anamnestic general or local risk situation, among others: Anti-angiogenic therapy, History of local radiation therapy, severe coagulation disorder, unadjusted diabetes mellitus, malignant diseases * Acute gingivitis or advanced periodontitis * Participation in an ongoing drug trial (various drugs may distort the result, such as bisphosphonates, cortisone, chemotherapeutics, angiogenesis inhibitors) * heavy smokers (\> 10 per day) * Acute or chronic infections (osteomyelitis) at the surgical site * metabolic diseases (diabetes, hyperparathyroidism, osteomalacia) * Severe kidney dysfunction, severe liver disease * Patients with high-dose corticosteroid therapy * prolonged corticosteroid or radiotherapy in the oral cavity * autoimmune diseases * Pregnant or breastfeeding women

Design outcomes

Primary

Measure	Time frame	Description
Survival	1 year	Tooth survival

Secondary

Measure	Time frame	Description
Revascularisation	1 year	Occurrence of Revascularisation

Countries

Austria

Contacts

PRINCIPAL_INVESTIGATORPetra Rugani, DDS

Medical University of Graz

Outcome results