Degenerative Lumbar Spine Diseases
Conditions
Keywords
Posterior Lumbar Interbody Fusion (PLIF), Transforaminal Lumbar Interbody Fusion (TLIF), Implant Failure, Revision Surgery
Brief summary
This retrospective study is to determine whether age is a risk factor for postoperative complications in patients undergoing transforaminal lumbar interbody fusion; specifically whether the risk (odds) of implant failure and the need for revision surgery increases with age.
Detailed description
Spinal fusion is one of the most commonly performed surgical procedures for the treatment of degenerative spinal disease. Interbody fusion with cages reconstructs the anterior column through disc removal, allowing to maintain proper disc height despite weight bearing, while providing firm fixation of the spinal segments. Transforaminal lumbar interbody fusion (TLIF) has fewer complications and less intraoperative bleeding than posterior lumbar interbody fusion (PLIF). Elderly patients are at high risk for perioperative and postoperative complications after lumbar fusion. This retrospective study is to determine whether age is a risk factor for postoperative complications in patients undergoing transforaminal lumbar interbody fusion; specifically whether the risk (odds) of implant failure and the need for revision surgery increases with age.
Interventions
OTHERData collection (radiological parameters, outcome information) from electronic patient files in hospital data system
Collection of medical data and medical images (MRI, radiographs) of the lumbar spine and pelvis of patients having received TLIF with degenerative spinal diseases from the years 2015-2020 and statistical analysis of the coded data.
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Indications for TLIF surgery (e.g., degenerative disc disease, spondylolisthesis) * Existing preoperative upright standing sagittal plane X-ray of lumbar spine with clear visibility of pelvis, sacrum and femoral head * Existing preoperative MRI of the lumbar region with clear visibility of different fatty infiltration grade and stenosis degree * Complete follow-up at 3 months and 1 year postoperatively, including clinical and radiographic data
Exclusion criteria
* Neuromuscular diseases such as Parkinson's disease or multiple sclerosis according to our records * Preoperative infection and/or malignancy tumor with involvement of the bony or soft tissue structures of the lumbar spine * Presence of a documented consent dissent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of Implant failure | one time assessment at baseline | Number of Implant failure (screw loosening, cage subsidence, adjacent level alteration/ degeneration, spondylolisthesis degree, kyphosis of the adjacent intervertebral disc space, reduced height of intervertebral disc space) in relationship to age |
| Number of patients needing revision surgery | one time assessment at baseline | Number of patients needing revision surgery, in relationship to age |
Countries
Switzerland
Outcome results
None listed