Effectiveness of Port Site Bupivacaine Injection in Postoperative Pain Reduction After Lap. Chole

A Randomized Controlled Trial of Port Site Subcutaneous Injection of Bupivacaine to Determine the Effectiveness of Postoperative Pain Relief After Laparoscopic Cholecystectomy

Status

UNKNOWN

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05264805

Enrollment

166

Registered

2022-03-03

Start date

2022-03-31

Completion date

2022-09-30

Last updated

2022-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Postoperative

Keywords

#Post operative pain, #laparoscopic cholecystectomy

Brief summary

To determine the effectiveness of port site bupivacaine infiltration in postoperative pain reduction after laparoscopic cholecystectomy.

Detailed description

The study is being done to determine the effectiveness of port site bupivacaine infiltration in postoperative pain reduction after laparoscopic cholecystectomy.

Interventions

DRUG0.25% Bupivacaine

20ml of 0.25% Bupivacaine subcutaneous infiltration at port site wound.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

Group A: Study group: Patient receiving intervention i.e 20ml of 0.25% buvivacaine infiltration at laparoscopic port site. Group B: Control group: no intervention

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients of both the gender of age \>18 years and \<45years 2. Patients undergoing elective laparoscopic cholecystectomy under general anesthesia. 3. Patients with A.S.A grade I and II.

Exclusion criteria

1. Patients with known allergic reactions to local anesthetics. 2. Patients converted to open procedure. 3. Patients developing intra-operative complications. 4. Patients undergoing for laparoscopic cholecystectomy for acute cholecystitis. 5. Patients with obesity and chronic illness. 6. Patients with history of opioids, steroids, NSAIDs and alcohol use.

Design outcomes

Primary

Measure	Time frame	Description
Post laparoscopic port site pain assessment	Pain assessment from 0hour (patient received in recovery room) till 12hours postoperatively at interval of 3hours i.e. 0,3,6,9,12 hour	Pain assessment by Visual Analog Scoring system scoring from 0 to 10, where 0 means no pain and 10 means worst possible, unbearable excruciating pain.

Contacts

Primary ContactDr. Nida Shahid, MBBS, FCPS

nida-shahid2011@hotmail.com+923332358698

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026