Liver Diseases
Conditions
Brief summary
The purpose of the study is to study the muscle assessment score (MAsS, utilizing MRI, as an objective measure of frailty and muscle composition to serve as a predictor of morbidity and mortality in patients with liver disease.
Detailed description
Prospective study of patients seen at the Univ. of Chicago Medical Center hospital and ambulatory clinics. The assessment of the MAsS score will require an additional 8-10 minutes in the MRI for each patient already undergoing MRI exam. Four groups of pts. who are already scheduled for MRI for routine clinical purposes will be evaluated. 1. Pts. hospitalized with acute hepatic decompensation for whom MRI is otherwise indicated for clinical evaluation. 2. Pts. with hepatobiliary neoplasia 3. Pts.undergoing transjugular portosystemic shunt (TIPS) placement 4. Pts. with chronic liver disease undergoing magnetic resonance elastography for routine monitoring
Interventions
None listed
Sponsors
University of Chicago
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients who are already scheduled for an MRI for routine clinical purposes will be evaluated
Exclusion criteria
* \<18 yrs. of age
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Waitlist Mortality | Measured up to 10 years out from enrollment | Death prior to liver transplant or delisting from enrollment in the study |
Countries
United States
Contacts
Primary ContactOmar Jamil, MD
Backup ContactMaria Newsome
Outcome results
None listed