Neurosurgery, Postoperative Pain
Conditions
Brief summary
The proposed study intends to evaluate incidence of postoperative pain after neurosurgery. This study is likely to help in understanding of the magnitude of this problem in our country and inform about possible predictors which will help institute pre-emptive interventions to mitigate modifiable risk factors of pain after neurosurgery.
Detailed description
Data regarding potential risk factors for postoperative pain will be collected. Preoperative factors (preoperative pain, anxiety or depression, perception about surgery, age, gender, socio-economic status, educational level, domicile location, obesity, surgical site \[infratentorial or supratentorial or cervical, thoracic or lumbar\], use of steroids and analgesics), and intraoperative factors (scalp/ESP/caudal block, incision site infiltration, dose of analgesics such as opioids, paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs), co-analgesics such as nitrous oxide, gabapentionoids, dexmedetomidine, magnesium or lignocaine infusion, anti-epileptics, steroids, minimum alveolar concentration (MAC) of inhalational anesthetics, and duration of surgery and anesthesia) that are likely to be associated with occurrence of postoperative pain will be explored along with relationship between acute and persistent postoperative pain and between intraoperative nociception and postoperative pain.
Interventions
PROCEDURENeurosurgery
Neurosurgery
Sponsors
National Institute of Mental Health and Neuro Sciences, India
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* all eligible consecutive consenting adult patients aged \> 18 years with preoperative Glasgow Coma Scale (GCS) score of 15 undergoing elective craniotomies and spine surgeries
Exclusion criteria
* children, patients with GCS \< 15, patients not extubated within 2 hours of end of anesthesia and those who not able to respond to our questions on outcomes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain using Numerical Rating Scale | on days 1-3 after surgery | Acute postoperative pain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| duration of postoperative hospital stay in days | through hospital stay, an average of 10 days | duration of postoperative hospital stay in days |
| postoperative sleep quality using Likert 1-5 scale | Day 2 after surgery | sleep quality assessment |
| patient satisfaction using Likert scale 1-5 | Day 2 after surgery | patient satisfaction assessment using Likert scale 1-5 |
| Persistent postoperative pain using Numerical Rating Scale (NRS) | 3 and 6 months after surgery | Chronic Postoperative Pain measured using NRS (from 0 to 10, with 0 = no pain and 10 = maximal pain |
Countries
India
Outcome results
None listed