Sensory Ataxia
Conditions
Keywords
Vibro-tactile Stimulation, Neurorehabilitation, Ataxia
Brief summary
Interventional study of the effects of vibro-tactile feedback on behavioral deficits and learning during motor training in patients with sensory ataxia.
Interventions
Vibro-tactile stimulation will be administered to the feet of participants via C2 tactors (diameter: 3.05 cm, height: 0.79 cm, operating frequency: 200-300 Hz see https://www.eaiinfo.com/tactor-info/). Vibro-tactile stimulation will be triggered by force-sensing resistors (TEA CAPTIV T-SENS FSR, see https://www.teaergo.com/products/tea-captiv-t-sens-fsr/).
OTHERPlacebo Control
Devices mounted, no stimulation
Sponsors
German Research Foundation
National Natural Science Foundation of China
Universitätsklinikum Hamburg-Eppendorf
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
Assessment, motor training, data analyzes and group allocation are done by different persons. Participants as well as the assessor, the trainer and the investigator are blinded to the group allocation.
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Electrophysiological diagnosis of sensory ataxia * Age \>= 18, \<=80 * Existing declaration of consent
Exclusion criteria
* Pregnancy * Lacking capacity for consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in Timed Up-and Go Test | One day before (baseline) and one day after seven days of motor training | The Timed Up and Go test is a clinical test to assess a patient's mobility and risk of falling. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in 10-Meter-Walk Test | One day before (baseline) and one day after seven days of motor training | The 10-Meter-Walk Test is a performance measure used to assess walking speed in meters per second over a short distance. It can be employed to determine functional mobility and gait. |
| Change from baseline in Berg-Balance-Scale | One day before (baseline) and one day after seven days of motor training | The Berg-Balance-Scale (BBS) is used to determine a patient's ability to safely balance during a series of predetermined tasks. It is a 14 item list with each item consisting of a five-point ordinal scale ranging from 0 to 4, with 0 indicating the lowest level of function and 4 the highest level of function. |
| Change from baseline in Postural-Sway Test | One day before (baseline) and one day after seven days of motor training | The Postural-Sway Test is a common test of quiet stance balance. |
Countries
Germany
Outcome results
None listed