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Clinical Assessment of the Flash - Eye Movement Desensitization and Reprocessing

Clinical Assessment of the Flash Version of Eye Movement Desensitization and Reprocessing in Memory Distress: A Double Blinded Randomized Controlled Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05262127
Acronym
Flash-EMDR
Enrollment
90
Registered
2022-03-02
Start date
2021-09-01
Completion date
2023-03-01
Last updated
2023-01-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PTSD

Keywords

behavioural internet intervention, post-traumatic stress

Brief summary

To assess the Flash version of EMDR in reductions of the disturbance of upsetting memories at post-intervention, and 1-month follow up within a double-blinded, online 2-arm randomized controlled trial (RCT) with self-report outcomes. We will assess 45 per group, adequate for the detection of a medium effect size. This double-blinded, RCT will assess the comparative efficacy of these two online interventions designed to reduce memory disturbance.

Detailed description

This double-blinded, RCT compares the efficacy of 2 online interventions (Flash Version - EMDR; EMDR alone) designed to reduce memory disturbance.Inclusion Criteria: (1) approved for engagement assessment by the CloudResearch platform; (2) 25-60 years; 3) US-Canada residence; (4) a recalled disturbing memory of an event that has not repeated and was moderately upsetting, or greater when event occurred; (5) memory remains moderately upsetting or greater on recall. The disturbance of upsetting memories at post-intervention, and 1-month follow up will be assessed with self-report outcomes. We will assess 45 / group, adequate for the detection of a medium effect size. linked to an earlier memory (that is equally or more disturbing). Exclusion Criteria: Diagnosis of: (1) bipolar disorder; (2) borderline personality disorder; (3) obsessive compulsive disorder; (4) schizophrenia; (5) substance abuse/addiction in the past 3 months; (6) any suicidal ideation; (7) suicide attempt in the past 6 months. Interventions: Experimental participants observe video instructions of full FT, while controls receive an online intervention that follows traditional EMDR. Measures: Primary outcome: State Anxiety subscale of the State Trait Anxiety Inventory (STAI) at baseline, post-intervention, and after 1-month follow up; Post Traumatic Stress Disorder symptoms (PTSD) measured by PCL-5 (1 month follow up). Secondary outcomes: the Subjective Units of Disturbance (SUDs) assessing change in immediately reported disturbance of recalled memories (baseline and post-intervention); depression measured by Patient Health Questionnaire (PHQ9) and Positive-Negative Affect measured by the Positive and Negative Affect Scale (PANAS).

Interventions

BEHAVIORALFlash Version of EMDR

EMDR and the inclusion of a positive engaging focus generated autonomously by participant

Sponsors

York University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Masking description

Participants, assessors and care providers (if participants are in treatment) are masked to trial allocation.

Intervention model description

Parallel group, double-blind randomized controlled trial

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Moderately upsetting or \> memory of an event that occurred \> 2 years ago and has since not repeated * Moderately upsetting or \> memory remains moderately upsetting when recalled * Memory is not tied to an earlier memory that is equally disturbing or \>

Exclusion criteria

* Bipolar Disorder * Borderline Personality Disorder * Obsessive-Compulsive Disorder * Schizophrenia * Substance Abuse/Addiction in past 3 months * Suicidal ideation or attempted suicide in the past 6 months

Design outcomes

Primary

MeasureTime frameDescription
PTSD Checklist for DSM-5 (PCL-5) 1 - 441 month follow upSelf Report Questionnaire
State-Trait Anxiety Inventory - State 0 - 80.1 month follow upSelf Report Questionnaire

Secondary

MeasureTime frameDescription
Patient Health Questionnaire 0 - 271 month follow upSelf Report Questionnaire
Positive and Negative Affect Schedule 20 - 1001 month followupSelf Report Questionnaire

Countries

Canada

Contacts

Primary ContactPaul Ritvo, PhD
pritvo@yorku.ca4165808021
Backup ContactNazanin Babaei, BSc
nazaninb@my.yorku.ca4167362100

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 9, 2026