Diffusion Tensor Imaging, MRI, Tractography
Conditions
Brief summary
Primary and secondary brain tumors are challenging pathologies regarding diagnosis and treatment. MRI is widely used in the imaging evaluation and surgical planning, due to its spatial resolution and ability of tissular characterization. In this study patients with suspected brain tumors, confirmed by routine MRI evaluation (T1, T2, T2\*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation. By analyzing collected data from MRI evaluation and patient records regarding surgical and histopathological data our aim is to investigate derived imaging biomarkers with impact in the surgical planning and rehabilitation of the patients.
Interventions
DIAGNOSTIC_TESTMRI
In this study patients with suspected primary and secondary brain tumors, confirmed by routine MRI evaluation (T1, T2, T2\*, FLAIR, T1 with contrast sequences) will undergo DWI and DTI evaluation.
Sponsors
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* brain tumors confirmed by routine MRI evaluation * surgical treatment with histopathological diagnosis
Exclusion criteria
* MRI contraindications * past or present neurological or neurosurgical condition, beside the tumor * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tract damage | 3 months | Assess the damage of tracts at baseline preoperative |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Craniotomy size | 3 months | Assess the size of craniotomy in patients with postoperative CT follow-up |
Countries
Romania
Contacts
Primary ContactMihail Porutiu
Backup ContactMircea Buruian
Outcome results
None listed