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Prognosis of Geriatric Patients 1 Year After Hospitalization for COVID-19

Prognosis of Geriatric Patients 1 Year After Hospitalization for COVID-19

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05261061
Acronym
PROVID-Ger
Enrollment
1000
Registered
2022-03-02
Start date
2022-07-31
Completion date
2022-12-31
Last updated
2022-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Keywords

COVID-19, 1-year prognosis, older patients

Brief summary

Old patients hospitalized in Acute Geriatric Units are characterize by advanced age, frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy. Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors). For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.

Detailed description

Old patients hospitalized in Acute Geriatric Units are characterize by advanced age (average 85 years), frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy.These particular state leads to multiple decompensations and the reason for initial hospitalization is often only the tip of the iceberg. Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors). For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). This excess mortality is all the more surprising as these patients seem to have fewer comorbidities than those usually hospitalized in acute geriatric units. Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.

Interventions

None listed

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
75 Years to No maximum

Inclusion criteria

* Age \>=75 years * Hospitalized for medical reason in acute geriatric unit * Alive at hospital discharge

Exclusion criteria

* Patients hospitalized for surgical reason * Patients under legal protection * Patient refusal

Design outcomes

Primary

MeasureTime frame
One-year mortality1 year

Secondary

MeasureTime frameDescription
Activity of daily living (ADL) at 1 year1 year
SF-12 at one year1 yearQuality of life
Clinical Frailty Scale (CFS) at one year1 year
rehospitalization at one year1 year

Countries

France

Contacts

Primary ContactHélène VALLET, MD, PhD
Helene.vallet@aphp.fr+33149282042

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026