Mapping 3D Bladder

Feasibility of Spatially Registered Endoscopy for Mapping Bladder Mucosal Disease Into Radiation Planning Morphologic Imaging

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05260788

Enrollment

Registered

2022-03-02

Start date

2022-03-31

Completion date

2025-03-31

Last updated

2022-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder Cancer

Brief summary

This is a single centre, single arm feasibility study assessing the feasibility of using computer vision methods to recreate the 3D bladder shape and to then map the cystoscopy images onto this bladder shape. If feasible, this 3D reconstructed shape would be spatially registered to radiological images (CT, MR) that are then used during radiation treatment planning. This analysis would not be used for making any clinical treatment decisions on the patient.

Interventions

PROCEDURECystoscopy

Standard of care cystoscopy procedure

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

* 18 years of age or older. * Clinical suspicion or histologic diagnosis of bladder tumour suitable for endoscopic evaluation. * Intention to treat using external beam radiation therapy as part of standard of care. * Ability to provide written informed consent to participate in the study.

Exclusion criteria

* Prior complete or partial radiation therapy to bladder. * Contraindications to radiation therapy as determined by the treating physician. * Concurrent illness or condition that precludes subject from undergoing endoscopy or CT scanning.

Design outcomes

Primary

Measure	Time frame	Description
Video recording of Cystoscopy	At study completion, up to 2 years	To determine the feasibility of using bladder endoscopic video images to reconstruct the three-dimensional shape of the bladder based on computer visions methods that employ feature extraction and triangulation and to map the endoscopy images onto the recreated 3D surface.
Contouring of 3D bladder rendering	At study completion, up to 2 years	To determine the feasibility of contouring the mucosal disease on the 3D bladder rendering.
Registering bladder shape	At study completion, up to 2 years	To determine the feasibility of registering the bladder shape to a CT/MR scan of the patient using deformable shape methods.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026