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Effect of Cranberry Extract on the Urinary System

Effects of Use of Cranberry Extract Instead of Antibiotics During Uncomplicated Urinary Tract Infection

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05260554
Enrollment
2
Registered
2022-03-02
Start date
2022-01-26
Completion date
2022-02-18
Last updated
2022-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Tract Disease, Cystitis, Antibiotic Reaction

Keywords

Urinary Tract Disease, Cranberry extract, Antibiotic, Cystitis

Brief summary

In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did not).

Detailed description

This study was Istanbul Kartal Dr. Lütfi Kırdar Training and Research Hospital Emergency Medicine Clinic and Kırklareli Training and Research Hospital Emergency Service and Internal Medicine Polyclinic. Our study; includes patients who applied to the Emergency Department and Internal Medicine outpatient clinic with the complaint of dysuria and had normal WBC, CRP, urea, and creatinine values in their analysis, and leukocyturia was found in the urine test. Two options were offered in the treatment to these patients. Vaccinium Macrocarpon Aiton preparation or fosfomycin was given for seven days. The patients were asked whether their complaints had decreased according to the Lykert-Type verbal scale at the time of admission and on the first, third, and seventh days. When the treatment was finished, leukocytes were checked in the urinalysis. This outcome was compared between the 2 treatment options. We also noted whether nausea.

Interventions

DRUGFosfomycin

In this group with urinary tract inflammation; Fosfomycin was prescribed for 7 days (3 doses, 2 days apart). There are 80 patients in total.

DIETARY_SUPPLEMENTCranberry

In this group with urinary tract inflammation; 7 days (used every day) cranberry tablet was given. There are 80 patients in total.

Sponsors

Kırklareli University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Older than 18 * who have urinary tract inflammation * who haven't kidney dissease previous

Exclusion criteria

* Younger than 18 * Who have kidney inflammation * Pregnant patients * Who have blood test abnormal (WBC, Ure, Creatin, CRP high level)

Design outcomes

Primary

MeasureTime frameDescription
Treatment time7 daysAfter 7 days of treatment, the 2 treatment options were compared with each other.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026