The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05260229

Enrollment

Registered

2022-03-02

Start date

2021-12-12

Completion date

2022-05-31

Last updated

2022-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Internal Carotid Artery Stenosis

Brief summary

The investigators plan to collect 30 participants with internal carotid artery stenosis to observed the relationship between the degree of internal carotid artery stenosis and fundus vessels （and blood flow）density before operation, and compared with participants without internal carotid artery stenosis.The fundus blood flow density will be observed after intervention operation in order to see whether the operation is effective to improve the density of fundus vessels and blood flow or not.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

45 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients who have been diagnosed with carotid artery stenosis and need surgery; 2. Patients whose vision won't get worse soon; 3. Patients have not had any eye surgeries; 4. Patients with complete profile.

Exclusion criteria

1. Patients with severe systemic disease; 2. Patients with poor dioptric stroma; 3. Patients with nystagmus; 4. Patients with incomplete profile.

Design outcomes

Primary

Measure	Time frame	Description
The differences of perfusion density in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company	2022-01-31	The perfusion density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the not-significant narrowing side，or the perfusion density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the side with carotid artery stenosis of different degrees.
The differences of vessel density in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company	2022-01-31	The vessel density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the not-significant narrowing side，or the vessel density differences between the fundus vessels（both the macula area and the optic disc area） on the carotid artery stenosis side and the side with carotid artery stenosis of different degrees.
The perimeter and area of the fovea avascular zone（FAZ）in the Forum of the optical coherence tomography angiography（OCTA ）of Zeiss Company	2022-02-14	The differences between the perimeter and area of the fovea avascular zone（FAZ） of the carotid artery stenosis side before and after interventional surgery.

Countries

China

Contacts

Primary ContactYan Cui, doctor

cyeleanor@163.com（+86）18560088136

Outcome results