Characteristics of Pneumothorax Associated With Transthoracic Percutaneous Lung Biopsy in Standard of Care

Characteristics of Pneumothorax Associated With Transthoracic Percutaneous Lung Biopsy in Standard of Care: a Retrospective Study in 6 Centers

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05259293

Acronym

PNOrate

Enrollment

243

Registered

2022-02-28

Start date

2021-12-09

Completion date

2022-12-31

Last updated

2024-09-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumothorax Iatrogenic Postprocedural

Keywords

interventional radiology, iatrogenic pneumothorax, transthoracic lung biopsy, pneumothorax rate, pneumothorax characteristics, patient management

Brief summary

The number of lung biopsies has increased steadily in recent years. Pneumothorax is the most common complication of a lung biopsy and can occur during the procedure, immediately after the procedure or within a few hours (delayed pneumothorax). The incidence of pneumothorax in the literature is very different from one study to another: it has been reported to be from 9 to 54% in patients undergoing percutaneous transthoracic needle biopsy. This difference of incidence could be explained by the absence of consensus for the definition of an iatrogenic pneumothorax. The characteristics of pneumothorax and the management of patients with iatrogenic pneumothorax will be evaluated in different centres in a retrospective manner. This study will contribute to refining the criteria for defining pneumothorax occurring during lung biopsy and will provide a better understanding of the condition and its management.

Interventions

OTHERNo intervention - retrospective study

This is a retrospective study. No intervention.

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged 18 years old and more at the time of the biopsy procedure in year 2020 * Having had a pneumothorax following their transthoracic percutaneous lung biopsy in year 2020

Exclusion criteria

* Objection to the use of the data (French sites only)

Design outcomes

Primary

Measure	Time frame
Annual incidence rate of pneumothorax related to transthoracic lung biopsy on total number of lung biopsies	3 months

Secondary

Measure	Time frame
Annual incidence rate of hospitalisation in patients with pneumothorax related to lung biopsies	3 months
Annual incidence rate of drainage in patients with pneumothorax related to lung biopsies	3 months

Countries

France, Ireland, United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026