Diabetes Mellitus
Conditions
Keywords
Diabetes Mellitus, Glucose Metrics, Outcome Evaluation, Intensive Care Unit
Brief summary
The purpose of this study is to investigate the clinical outcomes and glucose control metrics of critically ill patients with previously undiagnosed diabetes compared to those with known diabetes at the time of admission to the intensive care unit (ICU).
Detailed description
This case control study compares previously undiagnosed diabetic patients (defined as HbA1c \> 6.5% and no history of diabetes), to those with known diabetes, using 1:1 matching. Patients met inclusion criteria by having HbA1c available on ICU admission and at least four blood glucose tests during their ICU stay. Primary outcomes included ICU length of stay and inpatient mortality. Secondary outcomes included glucose metrics: mean blood glucose, coefficient of variation and percentage of patients who developed hypoglycemia.
Interventions
DIAGNOSTIC_TESTDiabetes Diagnosis
HbA1c \> 6.5%
Sponsors
Stamford Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
20 * Patients admitted between 9/14/2011 and 11/30/19 with HbA1c available on admission and at least four documented blood glucose tests during their ICU stay.
Exclusion criteria
* Patients admitted for diabetic ketoacidosis. * Patients admitted to the ICU following cardiovascular surgery.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Inpatient mortality | 2011-2019 | Estimates the risk of short-term mortality based on data from the initial 24 hours of intensive care unit (ICU) admission. Acute Physiology and Chronic Health Evaluation (APACHE) IV |
| Length of hospital Stay | 2011-2019 | Total days spent admitted to the hospital |
Countries
United States
Outcome results
None listed