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Comparison of Combined Serratus Anterior Plane Block and Thoracic Paravertebral Block

Comparison of the Effects of Ultrasound-Guided Combined Serratus Anterior Plane Block and Thoracic Paravertebral Block on Postoperative Acute Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05255562
Enrollment
60
Registered
2022-02-24
Start date
2022-02-15
Completion date
2023-05-16
Last updated
2023-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Postoperative, Serratus Anterior Plane Block, Thoracic Paravertebral Block, Multimodal Analgesia, Thoracic Surgery, Video-Assisted

Brief summary

Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS. Analgesic methods such as thoracic paravertebral block (TPVB), intercostal block, serratus anterior plane block (SAPB), and erector spinae plane block (ESPB) are widely used for VATS. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In recent years, the frequency of application of plane blocks as a component of multimodal analgesia has been increased. ESPB and SAPB are some of them. There are two techniques for SAPB application. In Deep SAPB (DSAPB) application, a local anesthetic agent is given under the serratus anterior muscle. In the Superficial SAPB (SSAPB) application, the local anesthetic agent is given above the serratus anterior muscle. Since it is done by entering from the same point in two applications, it is possible to perform these two applications at the same time with a single needle entry. The mechanisms of regional analgesia techniques used after thoracic surgery operations are also different from each other. Therefore, it may be possible to obtain a more effective analgesic effect in patients by combining the mechanism of action of DSAPB and SSAPB, as in the multimodal analgesia method. This study seeks to evaluate the effect of TPVB and combined SAPB (CSAPB) after VATS.

Interventions

Combined deep and superficial serratus anterior plane block will be applied to the patients under real-time ultrasound guidance.

DRUGThoracic Paravertebral Block

Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.

Sponsors

Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* 18 to 65 years old * ASA physical status I-II-III * BMI 18 to 30 kg/m2 * Elective video-assisted thoracoscopic surgery

Exclusion criteria

* Patient refusing the procedure * Emergency surgery * Chronic opioid or analgesic use

Design outcomes

Primary

MeasureTime frameDescription
Pain Scores48 hours after surgeryPain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 8th, 16th, 24th and 48th hours after surgery.

Secondary

MeasureTime frameDescription
Morphine Consumption24 hours after surgeryMorphine consumption for 24 hours will be recorded

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026