Compliance, Magnetic Resonance Imaging, Biaxial Testing, Elastic Modulus
Conditions
Brief summary
The aim of our study is to assess a correlation between local patient specific elastic modulus distribution of the ascending aorta from a biaxial tensile test and MRI measurements of the elastic properties of the aorta. A total of 70 patients referred for ascending aorta (AA) replacement underwent a preoperative cardiac-MRI for the evaluation the elastic properties and ascending aorta tissue was collected for biaxial testing to obtain maximum elastic modulus
Detailed description
Observational and prospective trial on medical data only. The patients are operated of planned aortic aneurysm without additional intervention. The preoperative cardiac MRI are planned in standard of care.
Interventions
None listed
Sponsors
Centre Hospitalier La Chartreuse
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient referred for ascending aorta aneurysm requiering replacement * elective patient
Exclusion criteria
* claustrophobia * contraindication to performing cardiac MRI
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| aortic compliance of ascending aorta (mm2/mmHg) | preoperative cardiac MRI performing between 1 month and 1 day before surgery | aortic compliance is a local measurement of elastic properties which is obtained with cardiac MRI images by computer processsing |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| maximum elastic modulus (MPa) of ascending aorta | biaxial testing performing between 1 and 6 hours after procedure | maximum elastic modulus is a local measurement of elastic properties which is obtained by biaxial testing |
Countries
France
Contacts
Primary Contactmarie-catherine Morgant, MD
Outcome results
None listed