Chronic Diseases
Conditions
Keywords
Food safety, Food nutrition, Food contaminant, Mult-omics, Chronic diseases
Brief summary
The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.
Detailed description
Investigations of associations of food nutrition and safety factors with the risk of chronic diseases are limited and studies in China are still lacking. The investigators aim to collect basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors, and so on, to assess the association of food nutrition and safety factors including various food items, dietary fatty acids, and internal biomarkers of food contaminants such as acrylamide and 3-MCPD with various chronic diseases in a Chinese middle-aged and elderly population. We will use multi-omics technology to investigate the causal mechanisms. Results from this study will be valuable for chronic diseases prevention in China.
Interventions
None listed
Sponsors
Lanxi Red Cross Hospital
Lanxi Hospital of Traditional Chinese Medicine
Zhejiang University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
45 Years to 75 Years
Inclusion criteria
* Subject aged ≥45 and ≤74 years old * Subject has complete data on diet and follow-up time
Exclusion criteria
had the major illness that had made personal life disabled
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Numbers of participants with metabolic syndrome | From entry into the study baseline:2018 until 2023 | metabolic syndrome |
| Numbers of participants with obesity | From entry into the study baseline:2018 until 2023 | Obesity |
| Numbers of participants with diabetes | From entry into the study baseline:2018 until 2023 | Diabetes |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Numbers of participants died | From entry into the study baseline:2018 until 2023 | All-cause and cause-specific mortality |
| Numbers of participants with cardiovascular diseases | From entry into the study baseline:2018 until 2023 | Cardiovascular diseases |
Other
| Measure | Time frame | Description |
|---|---|---|
| Numbers of participants with fatty liver disease | From entry into the study baseline:2018 until 2023 | Fatty liver disease |
Countries
China
Outcome results
None listed