Pain, Postoperative
Conditions
Keywords
quadratus lumborum nerve block, analgesia, total hip arthroplasty, postoperative outcomes
Brief summary
The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip arthroplasty (THA).
Detailed description
Investigators will enroll subjects planned for primary THA and allocate them into receiving a QL block with either saline or ropivacaine. Primary outcome will be pain scores over the first 48 hours after surgery.
Interventions
DRUGActive Comparator
QL block with 0.25% ropivacaine
DRUGPlacebo Comparator
QL block with saline
Sponsors
University of California, Los Angeles
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult subjects undergoing elective primary total hip arthroplasty
Exclusion criteria
* patients age \< 18, * documented allergy to local anesthetic * presence of peripheral neuropathy * patients with current long term opioid use defined as receiving an opioid on most days in a 90 day period * patients with a contraindication to spinal and regional anesthesia such as coagulopathy or infection at the site of the regional technique.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain score | Up to 48 hrs post op | Pain scores will be assessed over 48hrs postop using the visual analog score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Opioid usage | Up to 48 hrs post op | Total morphine-equivalent will be calculated at 0-24hrs and 24-48hrs postop. |
| Time to first stand | Up to 1 week post surgery | The period between the end of surgery and the patient's first successful attempt at standing, with or without the assistance of devices (i.e. walker, cane) or staff assistance. |
| Time to first ambulation | Up to 1 week post surgery | Time to first ambulation of 50 feet or more, with or without the help of assist devices (i.e. walker, cane) or staff assistance. |
| Ambulation distance | Up to 1 week post surgery | This data point will be measured in feet and will be determined by the distance ambulated during the patient's first ambulation attempt after surgery, regardless of the length of ambulation (This distance will be counted regardless of whether the patient reaches the 50 feet requirement to be counted as the "time to first ambulation). |
| Length of hospital stay | Until discharge from hospital, up to 1 week post surgery | Number of days in the hospital from postoperative day 0 to discharge |
| Patient satisfaction | Until day of discharge from the hospital, up to 1 week post surgery | Patient satisfaction score will be assessed on day of discharge as measured by a 5-point scale with 1 = terrible, 2 = poor, 3 = satisfactory, 4 = good, and 5 = excellent. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORPamela Chia, MD
University of California, Los Angeles
Outcome results
None listed