Hospitalization
Conditions
Keywords
orthostatic hypotension, Internal Medicine
Brief summary
The two scientific societies FADOI and SIIA have decided to start a collaborative study protocol that, through the application of a simple and homogeneous method to diagnose orthostatic hypotension, aims to estimate prevalence, conditions associates and outcomes in a cohort of patients admitted to Internal Medicine Departments and with known or newly diagnosed arterial hypertension.
Detailed description
The IP-OP study, is an observational, multicenter, prospective, national study that provides for the involvement of 34 Operating Units of Internal Medicine, and the recording of data relating to 1000 hospitalized adults. The clinical data of all consecutive patients diagnosed with arterial hypertension hospitalized in Internal Medicine and able to take the erect station will be collected.
Interventions
There will not be any experimental intervention. The study will be conducted according with normal clinical practice
Sponsors
Fadoi Foundation, Italy
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years * Presence of arterial hypertension (known or discovered at hospitalization) * Signature of Informed Consent
Exclusion criteria
* Patients unable to take the standing station for a few minutes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical conditions ( physiological parameters, copatologies) associated with the presence of orthostatic hypotension | 4 months | Identification, through a multivariate analysis, of the clinical conditions associated with the presence of orthostatic hypotension in the population of hypertensive patients admitted to Internal Medicine |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Gender differences in prevalence and conditions associated with orthostatic hypotension | 4 months | Assessment of possible gender differences in prevalence and conditions associated with orthostatic hypotension |
| Level of cognitive impairment of the subjects studied, and relationship with orthostatic hypotension | 4 months | Evaluation in the initial visit of the level of cognitive impairment of the subjects studied, and relationship with orthostatic hypotension |
| Relationship between orthostatic hypotension and a Fragility Index | 4 months | Evaluation of the relationship between orthostatic hypotension and a Fragility Index |
| Prevalence of orthostatic hypotension | 4 months | Prevalence of orthostatic hypotension among hypertensive patients admitted to Internal Medicine |
| Prescription drugs on the presence and severity of hypotension Orthostatic | 4 months | Analysis of the impact of prescription drugs on the presence and severity of hypotension Orthostatic |
| Presence of orthostatic hypertension | 4 months | Evaluation of the presence of orthostatic hypertension |
| After 6-12-24-36 months from the index hospitalization, of the state of health of all the subjects evaluated | 6-12-24-36 months from hospitalization | Evaluation, after 6-12-24-36 months from the index hospitalization, of the state of health of all the subjects evaluated, reporting the possible onset of falls, major cardiovascular events (stroke, TIA, myocardial infarction, arrhythmias) or death. |
| Relationship between orthostatic hypotension and comorbidity by calculating the index of Charlson comorbidity | 4 months | Evaluation of the relationship between orthostatic hypotension and comorbidity by calculating the index of Charlson comorbidity |
Countries
Italy
Outcome results
None listed