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Postoperative Hypoxia and Body Position

Postoperative Hypoxia and Body Position

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05246605
Enrollment
34
Registered
2022-02-18
Start date
2022-03-16
Completion date
2023-12-01
Last updated
2023-03-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Surgery, Hypoxia, Postoperative Complications

Brief summary

The study aims at investigate whether the oxygen partial pressure is improved in the prone position postoperative after abdominal surgery. Included are 50 adults operated with abdominal surgery. The Intervention is turning from supine to prone position and then back to supine position while measuring whether an improvement occurs in oxygen saturation and oxygen partial pressure, or not.

Detailed description

Postoperative hypoxia complicates 30% - 50% of abdominal surgeries. The cause of postoperative restrictive lung function and hypoxia is unknown. Previous studies report that oxygen partial pressure decreases by an average of 2 kPa after abdominal surgery, while carbon dioxide partial pressure is unchanged and vital capacity decreases by 35%. Patients are operated and treated in the post anesthesia care unit in the supine position. The study aims at investigate whether the oxygen partial pressure is improved in the prone position postoperative after abdominal surgery or not. Inclusion: 50 adults operated with abdominal surgery. Exclusion: Esophageal surgery, Abdominal vessel surgery. Decline participation. Intervention: turning from supine to prone position and then back to supine position again. Primary outcome: Change in oxygen saturation and oxygen partial pressure. Secondary outcome: Change in carbondioxide partial pressure Procedures: Partial blood gas is taken before surgery. On the day of surgery or the day after: starting in supine position with continuous measurements of oxygen saturation from pulse oximetry, transcutaneous carbon-dioxide partial pressure and blood gas. Then turning to prone position and then back to supine position.

Interventions

OTHERchange in body position

changing from supine to prone position and the back to supine

Sponsors

Umeå University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Being operated within 2 in the abdomen because of upper gastrointestinal surgery, colorectal surgery, urological surgery or emergency surgery * Must be able to turn from supine position to prone position in the bed

Exclusion criteria

* Esophageal surgery, Abdominal vessel surgery. * Decline participation.

Design outcomes

Primary

MeasureTime frameDescription
Mean change in oxygen partial pressure in supine vs. prone position.Through study completion, an average of 1 yearOxygen partial pressure
Mean change in oxygen saturation pressure in supine vs. prone position.Through study completion, an average of 1 yearOxygen saturation

Secondary

MeasureTime frameDescription
Mean change in carbon dioxide partial pressure pressure in supine vs. prone position.Through study completion, an average of 1 yearCarbon dioxide partial pressure

Countries

Sweden

Contacts

Primary ContactKarl A Franklin, Prof
karl.franklin@umu.se+46 90 7850000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026