Preoperative Magnetic Resonance Imaging Abnormalities Predictive of Lumbar Herniation Recurrence

Preoperative Magnetic Resonance Imaging Abnormalities Predictive of Lumbar Herniation Recurrence Following Surgical Repair

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05246241

Enrollment

188

Registered

2022-02-18

Start date

2021-04-01

Completion date

2022-02-01

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Disc Herniation

Brief summary

There are currently no standard criteria for evaluating the risk of recurrent disk herniation following surgical repair. This study investigated the predictive values of five presurgical imaging parameters, paraspinal muscle quality, annular tear size, Modic changes, modified Pfirrmann's disc degeneration grade, and presence of sacralization or fusion. Clinical status and MRI findings were evaluated before surgery and 4, 12, and 24 months post-surgery using a Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and Short Form 36 (SF36).

Interventions

DEVICEmagnetic resonance imaging

Preoperative magnetic resonance imaging

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* first operation for a single-level lumbar disk herniation * no concurrent spinal pathology such as stenosis, spondylolisthesis, or deformity * complete data on clinical and radiological parameters

Exclusion criteria

* the operation was for multi-level pathologies * recurrent surgery * exhibited concurrent spinal pathology * was missing or incomplete clinical and radiological data

Design outcomes

Primary

Measure	Time frame	Description
sacralization or fusion	Preoperative 1 month	MRI findings
Annular tear size	Preoperative 1 month	With computer as millimeter
Modic changes	Preoperative 1 month	Modic classification
Disc degeneration grade	Preoperative 1 month	modified Pfirrmann's classification
Paraspinal muscle quality	Preoperative 1 month	Simplified 3-tier classification

Secondary

Measure	Time frame	Description
Oswestry Disability Index (ODI)	4, 12, and 24 months after surgery	Oswestry Low Back Pain Disability Questionnaire
Short Form 36 (SF36)	4, 12, and 24 months after surgery	SF-36 Questionnaire
Visual Analog Scale	4, 12, and 24 months after surgery	0-10 numerical scale (0=no pain, 10 =the worst pain)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026