Gastric Emptying Time
Conditions
Keywords
Gastric volume, Gastric emptying time, Antral cross-sectional area (ACSA), Obese pediatric patients
Brief summary
In the recent literature, pre-operative fasting times for pediatric patients are limited to one hour for clear fluids. Studies related to gastric emptying times mostly searched for normal-weight children. These studies have claimed that 3 mL/kg clear fluid can be allowed up to 1 hour before surgery. There is a lack of interest in the gastric emptying time of obese pediatric patients during the preoperative period. In addition, there is controversy about gastric emptying times of obese healthy children. Some research committed the decrease of gastric emptying because of a high level of sensitivity to cholecystokinin, while others postulated that no change in gastric emptying time of obese children compared to normal weight. The aim of this trial is to compare the gastric volume and gastric emptying time after ingestion of 3 mL/kg clear fluid in obese and non-obese pediatric patients in the pre-operative period.
Detailed description
After receiving informed consent from the children and their families, American Society of Anesthesiologists (ASA) 1-2 pediatric patients between 6-14 years, who will recruit for elective surgery will be included for this study. The children over 95% percentile will be accepted as obese. After, the basal gastric volume will be calculated with the help of Ultrasonography (USG). The children will receive oral 3 mL/kg(max 250 mL) 5% dextrose .USG evaluation will be made every 5 minutes until the gastric volume reaches the basal level. Children reaching basal gastric volume will be accepted as suitable for the surgery. The aim of this study is to compare the gastric volume and gastric emptying time after ingestion of 3 mL/kg clear fluid in obese and non-obese pediatric patients in the pre-operative period.
Interventions
DRUG5% Dextrose
All the patients will receive oral 3mL/kg 5%Dextrose
Sponsors
Karaman Training and Research Hospital
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Pediatric patients will be divided into two groups as obese and non-obese. Children above the 95% percentile will be considered as obese.
Eligibility
Sex/Gender
ALL
Age
6 Years to 14 Years
Healthy volunteers
No
Inclusion criteria
* ASA physical state I or II * Age 6 to 14 years. * Gender: both sexes. * Scheduled for non-Gastrointestinal Tract elective day-case surgery under general anesthesia.
Exclusion criteria
* Parent/ care giver refusal * Ages \< 6 or \> 14 years old * Children with gastro-esophageal reflux disease * Renal failure * Diabetes mellitus * Cerebral palsy patients * Mental retardation * Esophageal strictures, achalasia or any intestinal disease that may impair the gastric emptying. * Gastrointestinal system surgery and neurosurgical patients * Emergency surgery * Violation of the prescribed fasting times * Refusing to drink prescribed clear fluid
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gastric emptying time | 90 minute | Time until the gastric volume reaches the baseline level again. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Antral cross-sectional area | 90 minute | Antral cross-Section Area (ACSA) (cm2) maximal anteroposterior diameter (D1) and longitudinal diameter (D2) will be measured with ultrasound and calculated with that mathematical formula: ACSA(cm2) = Π x D1 x D2 / 4 |
Other
| Measure | Time frame | Description |
|---|---|---|
| Gastric emptying half-time ( t 1/2) | 90 minute | Time required for ACSA to return to half maximum value. |
| Gastric volume | 90 minute | The mathematical model will be used which was reported by Perlas and colleagues based on gastroscopic fluid assessment will be used for the calculation of gastric volume (mL) from ACSA. GastricVolume(mL) = 27.0 + 14.6 x ACSA(cm2) -1.28 x Age(years) |
Countries
Turkey (Türkiye)
Outcome results
None listed