Erectile Dysfunction, PRP
Conditions
Brief summary
RPR contains rich-in growth factors and has the properties of helping tissue regeneration and nerve repair. In theory, it is possibility of curing ED.
Detailed description
There are many reasons of erectile dysfunction(ED). If left untreated, there is a major impact on relationships, self-esteem, and overall health. RPR contains rich-in growth factors and has the properties of helping tissue regeneration and nerve repair. Its mechanism is to promote the regeneration of blood vessels in the cavernous body of the penis, increase blood circulation, and then help erection, increase penile stiffness and improve the phenomenon of premature ejaculation. The main purpose of this study is to study the safety and effectiveness of PRP injection for the treatment of ED.
Interventions
BIOLOGICALPRP
4\ 6ml autologous platelet rich plasma injection every 14±2 days for a total of 5 injections.
Sponsors
National Taiwan University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Male * Between 20 and 70 years old * Sexual dysfunction exists for at least 6 months * IIEF-5 score 8-2 * Sign an informed consent form
Exclusion criteria
* Ever radical prostatectomy or extensive pelvic surgery * Radiation therapy to the pelvic area within 12 months before recruiting * Cancer * Nervous system diseases that affect erectile function * Have any blood disease * History of coronary artery disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| International Index of Erectile Function(IIEF-5) | Change from 0 week at 4,8,12,24,48 weeks | The possible scores for the IIEF-5 range from 5 to 25, and ED was classified into five categories based on the scores: severe (5-7), moderate (8-11), mild (12-21), and no ED (22-25). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Erection Hardness Score(EHS) | Change from 0 week at 4,8,12,24,48 weeks | EHS can be a helpful tool to evaluate ED - a man's inability to get or maintain an erection firm enough for sex. To select one of the following options: 0 Penis does not enlarge 1. Penis is larger, but not hard 2. Penis is hard, but not hard enough for penetration 3. Penis is hard enough for penetration, but not completely hard 4. Penis is completely hard and fully rigid |
| Duplex - Peak systolic velocity(PSV) | 0,16 weeks | To assess penile hemodynamics - Penile arterial blood velocity record (cm/s) |
| Duplex - Resistance index(RI) | 0,16 weeks | To assess penile hemodynamics - Penile vascular resistance Index |
Countries
Taiwan
Contacts
Primary ContactI-Ni Chiang, MD
Outcome results
None listed