Head and Neck Cancer
Conditions
Keywords
Supportive Care, Older Patients with Head and Neck Cancer Receiving Radiation and Chemotherapy, 22-016
Brief summary
The researchers are doing this study to see whether geriatric co-management or geriatric guided supportive care are good approaches for managing side effects in older patients who have head and neck cancer and are receiving chemoradiation therapy. This study will provide valuable information about different ways to manage side effects in older patients receiving chemoradiation therapy.
Interventions
OTHERgeriatric co-management
Geriatric co-management involves a consultation with a geriatrician prior to initiating head and neck radiation and chemotherapy.
OTHERgeriatric guided supportive care
Geriatric guided supportive care will be carried out by oncologists. After the patient completes the eRFA, an automated report is generated that identifies the patient's geriatric deficits.
Sponsors
Memorial Sloan Kettering Cancer Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
The study design is a randomized pilot clinical trial with two arms. Enrolled patients are those aged ≥70 years with newly diagnosed or post-operative head and neck squamous cell carcinoma. Patients will be undergoing radiation with concurrent chemotherapy.
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 65 * Pathologically (histologically or cytologically) diagnosis of head and neck cancer of oral cavity, oropharynx, larynx, or hypopharynx * Patient will receive a 6 to 7 week course of intensity modulated radiation therapy and concurrent chemotherapy either in definitive or post-operative setting * Able to read and understand English * Able to provide informed consent
Exclusion criteria
* Patients who have previously consulted with or are followed by a geriatrician * Inability to use telemedicine if unable to present to clinic visits in person * Inability to complete the eRFA (patient is unable to comprehend or answer questions included on the eRFA) * Treatment with proton therapy * Patients on therapeutic clinical trials of experimental therapies or those not receiving standard of care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| proportion of patients with hospital admission (geriatric co-management arm) | 2 years | The proportion of patients hospitalized during the course of chemoradiation either at MSKCC or an outside hospital will be assessed for each arm. |
| proportion of patients with hospital admission (geriatric guided supportive care arm) | 2 years | The proportion of patients hospitalized during the course of chemoradiation either at MSKCC or an outside hospital will be assessed for each arm. |
Countries
United States
Outcome results
None listed