Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19

Imbalances of Regional Pulmonary Ventilation in Patients With Post-acute-COVID-19 Symptoms

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05238623

Enrollment

Registered

2022-02-14

Start date

2025-10-01

Completion date

2027-03-31

Last updated

2025-09-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19 Pneumonia, Electric Impedance, Post-acute COVID-19 Syndrome

Keywords

Electric Impedance, CT, Tomography, regional ventilation, post-acute-COVID-19 syndrome, post-COVID-19, EIT, electroimpedance tomography, long-COVID

Brief summary

Investigation of the correlation of CT-morphological changes of the lung compared to regional ventilation distribution on electrical impedance tomography in patients with post-acute-Covid-19 symptoms.

Detailed description

Prospective non-interventional, monocentric observational study on imbalances in regional lung ventilation compared to chest CT in post-acute-Covid-19. The aim is to verify the agreement between computerized tomography derived imaging variables and electrical impedance tomography in detecting lung ventilation imbalances. The primary study objective is to match CT morphological changes in regional ventilation in post-acute-COVID-19 patients and/or changes in lung function examination, with changes that can be visualized by electroimpedance tomography.

Interventions

DIAGNOSTIC_TESTadditional EIT Measurement

Patients who receive standard CT and pulmonary function testing also receive electroimpedance tomography measurement. The lunghealthy Patients in the control group only receive a EIT.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* all patients undergoing a Chest CT due to suspected post-acute-Covid-19-syndrome * \>18 years * informed consent.

Exclusion criteria

* trauma patients and patients with unstable spinal injuries or fractures * patients with an BMI over 50 * patients with uncontrolled body movements * Patients with a pacemaker

Design outcomes

Primary

Measure	Time frame	Description
Correlation between tomography and electroimpedance tomography	until May 2022	The primary study objective is to match CT morphological changes in regional ventilation in post-COVID patients and/or changes in lung function examination with changes that can be visualized by electroimpedance tomography.

Secondary

Measure	Time frame
Correlation between lung function testing and electroimpedance tomography	until May 2022

Countries

Germany

Contacts

Primary ContactJan-Christoph Lewejohann, Dr.

jan-christoph.lewejohann@med.uni-jena.de+49 3641 9 32 20 13

Backup ContactPhillip A. Reuken, Dr.

Philipp.reuken@med.uni-jena.de+49 3641 9 32 4504

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026