Kidney Stone, Nephrolithiasis
Conditions
Keywords
Kidney Stone, Nephrolithiasis
Brief summary
Nephrolithiasis is a disease caused by the formation of kidney stones in the urinary tract which can then partially or completely obstruct the latter causing an extremely sharp pain called renal colic. In industrialized countries, it affects 10 to 20% of the population, and is the most common kidney disease.The primary objective of this study is to identify the clinical, biological, genetic, molecular and environmental determinants predictive of recurrence of renal lithiasis. The study follow-up visit schedule corresponds to the visits usually scheduled as part of patient care: 1 year from the inclusion visit (A1), 3 years (A3) then 5 years (A5). Samples for research (additional volume of blood, urine) will be taken by a registered nurse along with the routine check-up samples.Samples intended for research will be sent by staff to the Biobanque de Picardie (CHU Amiens-Picardie) for processing and conservation.
Interventions
BIOLOGICALBlood and urine samples
Additional Blood and urine samples will be collected at inclusion, 1, 3 and 5 years follow up visits
Sponsors
Institut Pasteur de Lille
Université de Lille
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (≥18 years old), male or female , * Persons able to understand and object to the information provided (at the discretion of the investigator) * Patient affiliated to social security * Patient agreeing to sign the informed consent form * patient having presented at least one renal colic attack before inclusion
Exclusion criteria
* Pregnant or breastfeeding woman. * Persons deprived of liberty, * Adults under legal protection guardianship, or curators or unable to express their consent. * Patient refusing to participate in the study * Patient in an emergency situation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients with nephrolithiasis recurrence within 5 years of follow-up | at 5 years |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of patients with a deterioration in renal function | at 1 year | Occurrence of patients with a deterioration in renal function during follow-up |
| Occurrence of patients with diabetes | at 1 year | — |
| Occurrence of patients with osteopenia | at 1 year | Occurrence of patients with osteopenia during monitoring of bone mineral density with DXA |
| Occurrence of high blood pressure patients | at 1 year | — |
Countries
France
Contacts
Primary ContactDominique Eladari, Pr
Outcome results
None listed