Vaccine Reaction
Conditions
Brief summary
The study's objective is to test the hypothesis that immune system activation and subsequent systemic inflammation can be detected through continuously tracking multiple bio signals including physiologic variables (ECG, skin temperature and their derivatives) and behavioral variables (activity and sleep from accelerometers) collected during routine activities of daily living using wearable biosensors. In the sub-study, the objective is to explore the association between these objectively measured physiologic changes and vaccine-induced humoral and T-cell responses.
Interventions
None listed
Sponsors
physIQ, Inc.
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Is 18 years of age or older. * Is able to speak and read English. * Plan to receive either the Moderna or Pfizer vaccine (mRNA vaccine). * No known prior COVID-19 infection.
Exclusion criteria
* Known allergy to the adhesive used on the VitalPatch.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Collect bio signal data before and after vaccination in ~100 individuals using one or more wearable biosensors. | December, 2022 |
| Evaluate the relationship between the MCI and individual bio signals parameters and the subjective symptoms experienced by participants. | December, 2022 |
| Explore the association between these objectively measured physiologic changes and vaccine-induced humoral and T-cell responses. | December, 2022 |
Countries
Canada, United States
Contacts
Primary ContactMaged Gendy
Outcome results
None listed