Bacteremia
Conditions
Brief summary
The objectives of the retrospective cohort study is to describe the actual current practice of antibiotic treatment duration for bloodstream infections in critically ill patients at two tertiary hospitals (ICU Inselspital Bern and ICU CHUV Lausanne), to examine patient, pathogen and infectious syndrome factors associated with selection of shortened treatment duration, and to describe the expected time course of clinical resolution among bacteremic patients.
Interventions
DIAGNOSTIC_TESTBlood Culture
Blood Culture
Sponsors
Insel Gruppe AG, University Hospital Bern
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patient has a positive blood culture with a pathogenic organism Patient is critically ill at the time the blood culture was collected as defined by the following: 1. was treated at the ICU/IMC at the time of blood culture collection; 2. or has been admitted to ICU/IMC in the 48 hours after blood culture collection
Exclusion criteria
1. Patient has a single positive blood culture with a common contaminant organism: * coagulase negative staphylococci; * Bacillus spp.; * Corynebacterium spp.; * Propionibacterium spp.; * Aerococcus spp.; * Micrococcus spp. 2. Explicit documentation that the patient does not want to participate in any study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Antibiotic Treatment Duration | Hospital discharge, expected to be on average ca. 15-20 days | Days of adequate antibiotic treatment in Patients with Bacteremia |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Days of ICU stay | ICU discharge, expected to be on average ca. 5-15 days | Days of ICU Stay in Patients with Bacteremia |
| Days of hospital stay | Hospital discharge, expected to be on average ca. 15-25 days | Days of Inhospital Stay in Patients with Bacteremia |
Countries
Switzerland
Outcome results
None listed