COVID-19, Hypoxemia, Hyperoxia, Hypoxia
Conditions
Keywords
Oxygen therapy, Automated titration
Brief summary
The aim of this study is to evaluate the impact of the FreeO2 system on the quality of the oxygen therapy in confirmed or suspected SARS-CoV-2 patients in the emergency department.
Detailed description
The aim of this study is to evaluate the impact of the FreeO2 system on the quality of the oxygen therapy in confirmed or suspected SARS-CoV-2 patients in the emergency department. The quality of oxygen therapy is evaluated by the time spent in the SpO2 target (+/- 2% SpO2 target), time spent in hyperoxemia (\> 5% SpO2 target), time spent in hyperoxemia (\<5% SpO2 target).
Interventions
Automated oxygen administration to maintain the SpO2 target at a predefined value during emergency length of stay
Sponsors
Laval University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hypoxemic patients on automated oxygen therapy during their emergency department stay * Confirmed or suspected SARS-CoV-2 patients in the emergency department
Exclusion criteria
* Patient on automated oxygen therapy in the emergency department without accessible data of the FreeO2 device.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Percentage of time in the saturation target in patients on automated oxygen titration device. | From the initiation of oxygen therapy with FreeO2 until the date of emergency department discharge or Stop of oxygen therapy with FreeO2 whichever came first, assessed up to 3 day after emergency admission | The percentage of time in target is defined by the percentage of time of (Target - 3% target) \< SpO2 value \< (Target + 3%) of the selected Spo2 target using automated oxygen titration device. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Oxygenation data - severe hypoxemia | From the initiation of oxygen therapy with FreeO2 until the date of emergency department discharge or Stop of oxygen therapy with FreeO2 whichever came first, assessed up to 3 day after emergency admission | The percentage of time in hypoxemia defined as a SpO2 value \< 85% |
| Oxygenation data - mild hypoxemia | From the initiation of oxygen therapy with FreeO2 until the date of emergency department discharge or Stop of oxygen therapy with FreeO2 whichever came first, assessed up to 3 day after emergency admission | The percentage of time in mild hypoxemia defined as a : (Target - 5% target) \< SpO2 value \< (Target - 2%) |
| automated oxygen therapy duration | From the initiation of oxygen therapy with FreeO2 until the date of emergency department discharge or Stop of oxygen therapy with FreeO2 whichever came first, assessed up to 3 day after emergency admission | Length of total time on automated oxygen therapy in the emergency department in hours. |
| Oxygenation data - hyperoxemia | From the initiation of oxygen therapy with FreeO2 until the date of emergency department discharge or Stop of oxygen therapy with FreeO2 whichever came first, assessed up to 3 day after emergency admission | The percentage of time in hyperoxemia defined as a SpO2 value \> 5% from the target. |
| Emergency length of stay. | From emergency departement admission until the date of emergency department discharge assessed up to 3 day after emergency admission | Time of stay in hours in the emergency department. |
| Hospital length of stay. | From emergency departement admission until the date of hospital discharge assessed up to 2 months after emergency admission | Time of stay in hours during hospitalisation Time of stay in hospitalisation setting (excluding the intensive care unit) and intensive care unit in days. |
| Orientation of care | From emergency departement admission until the date of hospital discharge assessed up to 2 months after emergency admission | Describe departement admission (emergency observation, general ward ,intensive care unit) |
| Ventilatory support | From the initiation of oxygen therapy with FreeO2 until hospital discharge, assessed up to 2 months after emergency admission | Need of change in ventilatory support device : (mechanical ventilation, non-invasive mechanical ventilation, high flow nasal canula, oxygen therapy) during emergency length of stay |
Countries
Canada
Contacts
Primary ContactFrançois Lellouche, MD, PhD
Backup ContactLéa Dallaire, MD
Outcome results
None listed