Orthostatic Hypotension
Conditions
Brief summary
The purpose of the study is to understand how blood pressure, heart rate, and symptoms of low blood pressure (such as dizziness or nausea) are affected by positional changes and exercise when on land or in the water for people who tend to experience orthostatic hypotension.
Interventions
BEHAVIORALWater exercise
Participants will be asked to sit and stand multiple times (before, immediately after, and 2 hours after a 15-minute walking session). The walking session will consist of 3 minutes of walking at a light intensity followed by 9 min of walking at a moderate intensity and a 3-minute cool down walking at a light intensity. This walking session will occur in a pool.
BEHAVIORALLand exercise
Participants will be asked to sit and stand multiple times (before, immediately after, and 2 hours after a 15-minute walking session). The walking session will consist of 3 minutes of walking at a light intensity followed by 9 min of walking at a moderate intensity and a 3-minute cool down walking at a light intensity. This walking session will occur on land.
Sponsors
University of Texas at Austin
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Self-report of dizziness upon standing (from sit or supine position) or known diagnosis of orthostatic hypotension * Able to stand independently for 3-5 consecutive minutes * Able to walk independently (with or without an assistive devise) * Medically stable for last month * Score of 3 or greater on Mini-Cog (standardized outcome measure to detect dementia) * Full coronavirus vaccination
Exclusion criteria
* Diagnosis of dementia * Contraindication for pool exercise (such as infected open wounds, fecal incontinence, diarrhea.)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Systolic blood pressure (mmHg) | <1 minute upon standing | Blood pressure will be taken with an automated blood pressure device |
| Diastolic blood pressure (mmHg) | <1 minute upon standing | Blood pressure will be taken with an automated blood pressure device |
| Self-reported orthostatic hypotension symptoms | 2 minutes | A self-reported instrument assessing symptoms from low blood pressure experienced upon standing or after prolonged upright activities. Possible scores range from 0 (no symptoms) to 10 (worse possible symptoms) |
Countries
United States
Outcome results
None listed