Colorectal Cancer
Conditions
Brief summary
Early detecting and removing of colorectal advanced adenomas can reduce incidence of colorectal cancer.Use of the fecal immunochemical test (FIT) for colorectal cancer (CRC) prevention is supported by previous studies.However existing instruments have low portability.The purpose of this study is to test the performance of a Point-of-care testing instrument for fecal Immunochemical test(FIT) .
Detailed description
Colorectal cancer (CRC) is the third most common cancer worldwide and has become a progressively important public health problem that inevitably leads to an increase in morbidity and medical costs. Therefore, many countries have a screening program in place to lower the incidence of CRC. Subjects with a positive fecal immunochemical test (FIT) have a much higher likelihood of advanced neoplasms than the general population.However existing instruments have low portability.The purpose of this study is to test the performance of a Point-of-care testing instrument for fecal immunochemical test (FIT).
Interventions
DIAGNOSTIC_TESTThe new instrument and colonoscopy with pathological examination
Detect hemoglobin in stool by the point-of-care testing instrument before colonoscopy, detect colon lesion using colonoscopy and pathological examination.
Sponsors
Shandong University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* People who use the new instrument for fecal immunochemical test(FIT) * People sign an informed consent form
Exclusion criteria
* People with history of surgery in any part of the large bowel; * People with symptoms including visible rectal bleeding, hematuria, hemorrhoid bleeds, severe and acute diarrhea and 7th type stool (Bristol feces score);
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic performance of advanced neoplasms | 4 months | The study is committed to test the diagnostic efficacy of the new instrument to advanced neoplasms.We will measure the sensitivity and specificity of the instrument |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Diagnostic performance of Colorectal Cancer | 4 months | The study is committed to test the diagnostic efficacy of the new instrument to colorectal cancer.We will measure the sensitivity and specificity of the instrument |
Countries
China
Contacts
Primary ContactSong yihao, BD
Backup ContactZhou ruchen, MD
Outcome results
None listed