Comparison of Intraoperative Intravenous Lidocaine Infusion and Transversus Abdominis Plane (TAP) Block for Post-operative Analgesia Following Laproscopic Cholecystectomy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05231941

Enrollment

Registered

2022-02-09

Start date

2022-02-25

Completion date

2022-10-17

Last updated

2024-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Operative Pain

Brief summary

This study is aimed to determine the post operative pain after laparoscopic cholecystectomy by dividing patients into three different group. Group A will receive lidocaine 2mg/kg bolus at induction followed by 1.5mg/kg/hr infusion. Group B will receive bilateral subcostal TAP block with 0.375% 20ml Ropivicaine on each side. Group C will not receive any additional pain regime apart from the routine intraoperative analgesics. Pain score will be assessed post operatively for 24 hours at regular intervals using visual analog score.

Interventions

DRUGLidocaine IV

Bolus and infusion of lidocaine will be administered

DRUGRopivacaine

Bilateral TAP block will be given to these patients

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Age group (18-65) * Undergoing elective Laproscopic Cholecystectomy * ASA status I or II

Exclusion criteria

* Participation in any other trial * Known hypersensitivity to study medications * Chronic Opioid used * Seizure disorder

Design outcomes

Primary

Measure	Time frame	Description
Pain score	On arrival in PACU (0 hours)	Pain score will be assessed using visual analog scoring system (0: No pain and 10: Worst Imaginable Pain)
Pain Score	At 24 hours	Pain score will be assessed using visual analog scoring system (0: No pain and 10: Worst Imaginable Pain)

Secondary

Measure	Time frame	Description
Post operative nausea and vomiting	On arrival, At 2 hours, 4 hours, 6 hours, 12 hours and 24 hours	Nausea and vomiting score would be assess using Bellville scoring system (0: No nausea or vomiting, 1: nausea, 2: nausea and belching, 3: vomiting)
Patient Satisfaction	At 24 hours or discharge	Patient satisfaction will be assessed on Likert Scale (Completely Disagree, Disagree, Neutral, Agree, Completely Agree)

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026