Hybrid Training, Metabolic Syndrome, Middle Aged, Non-alcoholic Fatty Liver Disease, Women's Health
Conditions
Brief summary
Modern living and physical inactivity results in many ailments, including obesity, non-alcoholic fatty liver disease (NAFLD), and inflammatory issues. Though there are a lot of studies on physical training, there is little detail on hybrid training or electrical and voluntary contractions of the musculature. This study investigated the efficiency of hybrid training in biochemistry, ultrasound, and proinflammatory outcomes in middle-aged sedentary and obese women with NAFLD.
Interventions
OTHERhybrid training
The experimental group trained two to three sessions of 45 to 50 minutes a week with a recovery of 24 to 48 hours between each session to burn 500 kcal. The first three weeks held hybrid training with a metabolic program and the other three weeks held a strength training program.
Sponsors
Niloofar Zareie Mohammad Zadeh
University of Sistan and Baluchestan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Parallel Assignment
Eligibility
Sex/Gender
FEMALE
Age
45 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Sedentary women with one to two exercise sessions or less per month * BMI equal to or above 30 kg/m-2 * WHR equal or above 0.85 m * Confirmed NAFLD, with grade 2 and 3 * Systolic blood pressure not less than 130 mm Hg and diastolic blood pressure not less than 85 mm Hg * Increased AST and ALT * Mean age 45-65 years
Exclusion criteria
* Use of 140 grams or more of ethanol per week * History of depression in the last 6 months * History of chronic or acute viral hepatitis * Drug-related liver disease and chronic liver disease * History of diabetes * Uncontrolled hypertension * Myocardial infarction * Chronic kidney disease * Hyperthyroidism or heart failure * Those who have weight loss programs or medical contraindications for physical training * Serious arterial hemorrhagic disorders * Serious neurological diseases * Advanced atherosclerosis * Elevated fever
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HDL Cholesterol Plasma | Pre-study | in mg/dl |
| Body Weight | Pre-study | in kg |
| Body Mass Index | Pre-study | in kg/m-2 |
| Aspartate transaminases | Pre-study | in u/l |
| Alanine transaminases | Pre-study | in u/l |
| Fasting blood sugar | Pre-study | in mg/dl |
| Proinflammatory cytokine (interleukin -6) | Pre-study | in pg/ml |
| Ultrasonic assessment | Pre-study | Grade of liver steatosis |
| WHR | Pre-study | Waist-to-hip ratio in cm |
| SBP/DBP | Pre-study | Systolic blood pressure/Diastolic blood pressure |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body Weight | six-week | in kg |
| Body Mass Index | six-week | in kg/m-2 |
| Aspartate transaminases | six-week | in u/l |
| Alanine transaminases | six-week | in u/l |
| Fasting blood sugar | six-week | in mg/dl |
| Proinflammatory cytokine (interleukin -6) | six-week | in pg/ml |
| Ultrasonic assessment | six-week | Grade of liver steatosis |
| WHR | six-week | Waist-to-hip ratio in cm |
| SBP/DBP | six-week | Systolic blood pressure/Diastolic blood pressure |
| HDL Cholesterol Plasma | six-week | in mg/dl |
Countries
Iran
Outcome results
None listed