Healthy Volunteers
Conditions
Brief summary
The aim of the present study is to test the effect of ingesting a multi-ingredient pre- exercise supplement containing caffeine, creatine, beta-alanine and L-Citrulline compared to a placebo, on endurance exercise performance.
Interventions
DIETARY_SUPPLEMENTLadder Supplement
Caffeine 200mg L-Theanine 200mg L-Citrulline 6g Creatine 5g Beta-Alanine 1.6g Phosphatidylserine 100mg
DIETARY_SUPPLEMENTPlacebo
Placebo
Sponsors
OpenFit LLC
University of Exeter
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Exclusion criteria
* Any diagnosed metabolic health condition * Pregnant * Non-habitual caffeine intake * Smoker * No endurance training * Diagnosed Cardiovascular disease * Recent history of musculoskeletal injury * Anti-depressant and anti-anxiety medication Inclusion criteria * Age 18-40 * Healthy * Highly trained endurance athletes (V̇O2max: males \>55 and females \>50 mL⋅kg bm-1⋅min-1) * Both males and females are allowed to participate. If females are on the oral contraceptive pill they are to be tested on consecutive weeks. If they are not on the oral contraceptive pill, then female subjects are to be tested every 4 weeks, at the same point of their menstrual cycle.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Exercise Performance | 15 Minitues | Work done during 15 min time trial (TT) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Motivation | 1 Hour | Visual analog scale |
| Rate of perceived exertion | 1 Hour | Visual analog scale |
| Gas analysis | 1 Hour | Analysis of expired gas |
| Alertness | 1 Hour | Visual analog scale |
Countries
United Kingdom
Outcome results
None listed