Decrease Artery Occlusion by Distal Radial Arterial Cannulation, Observational Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05230719

Acronym

DONATION-OB

Enrollment

2000

Registered

2022-02-09

Start date

2019-01-01

Completion date

2024-01-01

Last updated

2022-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome, Outcome, Fatal, Procedural Complication

Keywords

Distal Radial Access, Radial Artery Occlusion, Major Adverse Cardiovascular Events

Brief summary

The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications. Transradial access (TRA) reduces complications among patients undergoing percutaneous coronary procedures but is reported with the complication of radial artery occlusion (RAO) that limits the radial artery for future needs. Distal radial access (dTRA) has recently gained global popularity as an alternative access route for vascular procedures. Among the benefits of dTRA are the low risk of entry site bleeding complications, the low rate of radial artery occlusion, and improved patient and operator comfort. This study aims to reveal the feasibility and safety of dTRA and routine TRA procedures in acute coronary syndrome patients. The primary endpoints are forearm radical occlusion rate and major adverse cardiovascular events (MACEs) in the two groups. Investigators conduct this retrospected analysis to demonstrate the difference of the two procedure of Cannulation.

Interventions

PROCEDURERadial Artery Approach

dTRA or conventional TRA for radical artery approach

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Inclusion criteria

* presence of a pulse in the snuffbox

Exclusion criteria

* Absence of pulse * Ultrasound indication of arterial occlusion or severe calcification * Severe forearm artery malformation * Patients with severe liver and renal failure, or abnormal coagulation function * Established cardiogenic shock * History of previous coronary artery bypass grafting and radial artery use. * Raynaud's disease in the medical history

Design outcomes

Primary

Measure	Time frame	Description
Forearm radical	2 years	Doppler ultrasound to determine whether patients suffer forearm radial occlusion
MACEs	2 years	Major Adverse Cardiovascular Events, including cardiovascular death, myocardial infarction and heart failure.

Countries

China

Contacts

Primary ContactTangzhiming Li, PhD.

litangzhiming@126.com+86 18588269277

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026