Necrosis
Conditions
Brief summary
Primary Objective: The primary objective of this study is to develop and validate a clinical risk index score for identifying NSTIs in emergency general surgery patients being evaluated for a severe skin and soft tissue infection. Secondary Objectives: To describe the contemporary microbiology of NSTIs and explore the effects on outcomes and to identify predictors of amputation and mortality.
Detailed description
This study is designed as a multicenter, prospective, observational study. There will be no direct interaction with subjects and involves no interventions; study is conducted completely via review of electronic health records. Our site will only collect data from the Methodist Dallas Medical Center. We plan to complete the data collection and analysis by 12/30/2021.
Interventions
OTHERNecrotizing soft tissue infections (NSTIs)
There will be no direct interaction with subjects and involves no interventions; study is conducted completely via review of electronic health records. Our site will only collect data from the Methodist Dallas Medical Center.
Sponsors
Methodist Health System
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 89 Years
Inclusion criteria
* All adult patients (age ≥18 years old and ≤89 years old) with suspected or confirmed NSTI
Exclusion criteria
* Age \<18 years old and age \> 89 years * Pregnancy * Prisoners * Below ankle diabetic foot infections complicated by peripheral vascular disease * Burn wounds
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in the presence of necrosis | up to 30 days | presence of necrosis-dishwater fluid or deliquescent tissues |
| mortality length of time in hospital | 30-90 days | — |
Countries
United States
Contacts
Primary ContactCrystee Cooper, DHEd
Backup ContactAshley Haider
Outcome results
None listed