BK Viremia, Kidney Transplant Infection, Liver Transplant Infection, Polyomavirus Infections
Conditions
Brief summary
The human BK polyomavirus is a significant risk factor for renal transplant dysfunction and allograft loss. The prevalence of BK viremia (BKV) following kidney transplantation is estimated to be 10-20%.
Detailed description
The human BK polyomavirus is a significant risk factor for renal transplant dysfunction and allograft loss. The prevalence of BK viremia (BKV) following kidney transplantation is estimated to be 10-20%. Immunosuppression reduction is the management cornerstone for BKV and has been shown to be effective at clearing the virus while maintaining graft function in both kidney alone and simultaneous kidney-pancreas transplant recipients. However, there is a lack of published data on the prevalence and outcomes in simultaneous liver-kidney (SLK) transplant recipients.
Interventions
PROCEDURESimultaneous Liver-Kidney Transplant
Simultaneous Liver-Kidney Transplant
Sponsors
Methodist Health System
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Inclusion criteria
* Age 18 years or older * SLK recipients transplanted at MDMC between 2015-2020
Exclusion criteria
* Below 18 years of age * Patients who did not undergo SLK transplant at MDMC
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To characterize the prevalence of BKV in the SLK patient population at (Methodist Dallas Medical Center)MDMC. | over a 6-year period (2015 to 2020). | number of SLK transplant recipients who were transplanted at (Methodist Dallas Medical Center)MDMC |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORLori Kautzman, MD
Methodist Health System
Outcome results
None listed