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Epidemiology of Gunshot Wounds Injuries Admitted in ICU in France

Epidemiology of Gunshot Wounds Injuries Admitted in Intensive Care Unit in France: a Retrospective Multicenter Observational Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05224570
Acronym
GSW_in_ICU
Enrollment
120
Registered
2022-02-04
Start date
2015-01-01
Completion date
2022-06-17
Last updated
2025-12-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gunshot Wound

Brief summary

In civilian practice, the incidence of firearm violence depends on the country. In high income countries, most cases are reported in the USA or South Africa. In these countries, gunshot wounds (GSW) represent 20% of death cases in trauma centers, more than motor vehicle collisions. The mortality in civilian practice occurs during the first 24 hours following GSW, mainly due to hemorrhage and traumatic brain injury, though long term effects on physical and psychological outcomes have also been shown. Some factors of mortality specific to GSW have been established: multiples wounds, homicide vs suicide attempt, impact zone, or firearm caliber. Few specific guidelines have been published concerning civilian GSW management. These cases are mostly treated in standard guidelines, such as hemorrhagic shock or traumatic brain injury guidelines. As in other trauma mechanisms, the platinum ten minutes and golden hour concept is applicable. In Europe, the incidence of civilian GSW is much lower and few European studies have been published recently. Penetrating injuries in Europe are less likely to be GSW, and are more often self-inflicted than in the USA. In addition, European studies are heterogeneous, due to the difference in populations, healthcare systems and GSW being grouped with stabbing wounds under the label penetrating trauma. However, there is a global concern in Europe regarding a potential rise of GSW, with higher severity score than conventional trauma patients and often necessitate ICU admission. Studies analyzing data from different European countries show significantly different ICU admission rates for overall GSW, ranging from 17% up to 30%. Therefore, the investigators conducted a multicenter, retrospective study on four French University Hospitals aiming to describe the epidemiology (mortality and type of organ damage) and identify prognosis factors of civilian GSW admitted in ICU.

Interventions

None listed

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Admission for gunshot wound care in ICU between 1st of January 2015 and June 30th 2021 at Nimes University Hospital, Marseille North University Hospital, Montpellier University Hospital, Toulon Military Teaching Hospital. * Patient ≥ 15 years old

Exclusion criteria

* Patient \< 15 years old * Patient who objected to the use of their data.

Design outcomes

Primary

MeasureTime frameDescription
Mortalityday 28mortality rate at day 28 of patients admitted for Gunshot wounds

Secondary

MeasureTime frameDescription
SexDay 0To identify if sex is a prognosis factors of mortality of patients admitted for Gunshot
ComorbidityDay 0To identify if some comorbidities are some prognosis factors of mortality of patients admitted for Gunshot wounds (age, sex, comorbidity, type of gunshot, bullet impact zone, delay to reach hospital, biological parameters at ICU admission, use of antibiotics, blood transfusion, type of surgery, medical management, initiation of renal replacement therapy, length of ICU stay, ).
Type of gunshotDay 0To identify if the type of gunshot is prognosis factors of mortality of patients admitted for Gunshot wounds
Bullet impact zoneDay 0To identify if the impact zone is a prognosis factors of mortality of patients admitted for Gunshot wounds
Delay to reach hospitalDay 0To identify if the delay to reach hospital is a prognosis factors of mortality of patients admitted for Gunshot wounds
AgeDay 0To identify if age is a prognosis factors of mortality of patients admitted for Gunshot
antibiotics cureDay 0To identify if an antibiotic cure at admission is a prognosis factors of mortality of patients admitted for Gunshot wounds
Blood transfusionDay 0 to day 30To identify if a blood transfusion is a prognosis factors of mortality of patients admitted for Gunshot wounds
Type of surgeryDay 0 to day 30To identify if surgery type is a prognosis factors of mortality of patients admitted for Gunshot wounds
renal replacement therapyDay 0 to day 30To identify if initiation of renal replacement therapy is a prognosis factors of mortality of patients admitted for Gunshot wounds
length of ICU stayDay 0 to day 30To identify if length of ICU stay is a prognosis factors of mortality of patients admitted for Gunshot wounds
biological parameters at ICU admissionDay 0To identify if some biological parameters at admission are prognosis factors of mortality of patients admitted for Gunshot wounds

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026