Infection, Bacterial
Conditions
Brief summary
Irrational use of antibiotics is a one of the main health system problems,it leads to antibiotic resistance,increasing antibiotics side effects and the total cost. This study is a medication use evaluation study aims to evaluate intravenous clindamycin prescribing practice in critical care units in Alexandria Main University Hospital.
Interventions
it is a clindamycin use evaluation study
Sponsors
Alexandria University
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Adults 18 years old or more . * Patients on clindamycin as an empirical treatment. * Patients started clindamycin as an emperical treatment in other departments but the physician approved to continue it in critical care.
Exclusion criteria
* Children (less than 18 years old) * Patients started clindamycin as a defenitive treatment (based on microbiological culture results).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the number of prescriptions with appropriate indications of clindamycin will be counted during the retrospective observation of all prescriptions | 1 month | appropriateness of clindamycin indication will be determined according to IDSA guidelines. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the number of prescriptions with duplication of therapy with clindamycin will be counted during the retrospective observation of all prescriptions | 1 month | duplication of therapy means prescribing of clindamycin concurrently with another antibiotic to target the same microorganism. |
| the number of patients who had diarrhea as a main side effect of clindamycin | 1 month | diarrhea is a main side effect of clindamycin so in the study the number of patients who had diarrhea will be counted during the retrospective observation of all prescriptions |
| the number of patients who had severe drug interactions with clindamycin | 1 month | in the study the number of patients who severe clindamycin drugs interactions will be counted during the retrospective observation of all prescriptions |
| Total clindamycin DDD defined daily doses and clindamycin defined daily doses per 1000 patients days. | 1 month | Defined daily doses measurement of a drug is an indicator put by WHO , it indicates the consumption of this drug in a hospital or a department and defined daily doses per 1000 patients days indicates the consumption of this drug in relation to the total number of patients in a certain period of time. |
| to calculate the total cost of clindamycin. | 1 month | The cost of clindamycin treatment courses of all patients will be calculated in the Egyptian pound |
Countries
Egypt
Outcome results
None listed