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The Effects of Miminal Stimulation Protocol on Preimplantation Genetic Screening

The Effects of Miminal Stimulation Protocol on Clinical Outcomes of Advanced Maternal Aged Women With Preimplantation Genetic Screening

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05220995
Enrollment
200
Registered
2022-02-02
Start date
2021-05-15
Completion date
2022-01-25
Last updated
2022-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preimplantation Genetic Screening

Keywords

preimplantation genetic screening, gonadotropin dosage, euploidy rates

Brief summary

PGS has been the most effective method for embryo selection in IVF cycles. Euploidy rates decrease significantly with advancing maternal age (AMA). The dosage of gonadotropins also may be increased to recruit an adequate number of follicles in AMA women, minimal Stimulation Protocol (MSP) with the new combination of human menopausal gonadotrophin (hMG) and clomiphene citrate (CC) for controlled ovarian hyperstimulation is defined for poor ovarian response women. The aim of this study is to show minimal stimulation protocol affect euploidy and pregnancy rates in preimplatation genetic screening (PGS) cycles with single embryo transfer.

Interventions

GENETICprotocol

ovarian stimulation protocols on euploid rates were compared.

Sponsors

Gokalp Oner
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
38 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

Advanced maternal aged -

Exclusion criteria

Severe male factor, endometriosis, and absolute tubal factor were excluded in this study. \-

Design outcomes

Primary

MeasureTime frameDescription
euploid rates3 monthsthe effects of different stimulation protocols on euploid rates

Secondary

MeasureTime frameDescription
pregnancy rates3 monthsthe effects of different stimulation protocols on pregnancy rates

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026