Management of Pain Respiratory Distress at the End of Life in Newborn Palliative Care in the Delivery Room

Management of Pain Respiratory Distress at the End of Life in Newborn Palliative Care in the

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05220644

Acronym

PALLI-ACC

Enrollment

100

Registered

2022-02-02

Start date

2022-02-28

Completion date

2023-02-28

Last updated

2022-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Respiratory Distress

Keywords

newborn

Brief summary

The newborn feels pain and the newborn at the end of life, in the delivery room, is potentially exposed to pain and respiratory distress. Protocols for the management of end-of-life symptoms in the delivery room are used in current practice with very few validation studies. The protocol used in delivery rooms in Alsace uses fentanyl and midazolam intranasally. It has been used for 3 years and seems to provide satisfactory relief to newborn babies. In doing so, it seems to reassure parents about the quality of support and it seems to meet the expectations of professionals in these anxiety-provoking contexts. Scientific validation of these practices would allow wider dissemination to other maternity teams.

Interventions

PROCEDUREProtocols for the management of end-of-life symptoms

Application of the care protocol and data collection

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Premature or term newborn * In the delivery room * In palliative care * No parental opposition to data collection

Exclusion criteria

* Parental refusal or inability to express their consent * Minor parents * Very probable survival beyond the delivery room * Impossibility of giving informed information to the subject (subject in an emergency situation, difficulties in understanding the subject, etc.) * Subject under safeguard of justice * Subject under guardianship or curatorship

Design outcomes

Primary

Measure	Time frame	Description
Change in pain	1 day	Evaluate the effectiveness of the current protocol for the management of pain and discomfort related to end-of-life respiratory distress in newborns receiving palliative care in the delivery room with (Neonatal Facial Coding System) NFCS score
DRFV scores	1 day	Presence of DRFV with Silverman score

Countries

France

Contacts

Primary ContactPierre KUHN

Pierre.kuhn@chru-strasbourg.fr+33 3.88.12.77.85

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026