Recovery
Conditions
Keywords
Collagen peptides, Concurrent training, Ultrasound, MVC, RFD
Brief summary
The present study aims at investigating the potential influence of specific collagen peptides on recovery after exercise induced muscle damage with focus on long-term effects.
Interventions
DIETARY_SUPPLEMENTCollagen
Participants ingest 15 grams of either specific collagen peptides or Placebo daily
OTHERConcurrent training
Both arms undergo a 12-week trainingintervention 3x/week
Sponsors
CRI Collagen Research Institute GmbH
University of Vienna
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Masking description
Double-blind, randomized controlled trial
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* No subjective symptoms during physical exertion * Stable weight and dietary behaviour * Body Mass Index (BMI) between 18.5 and 24.9 * No extensive strength/endurance sports so far (less than 3 h/week) * No complaints during strenuous physical activity
Exclusion criteria
* Circumstances that impair/prevent sporting activity (e.g. chronic heart disease, arrhythmia, heart valve disease, arthritis etc.) * Intolerance/aversion to animal protein * Arterial hypertension (high blood pressure) (syst \> 200 mmHg and/or diast \> 105 mmHg) at rest * Presence of insulin-dependent diabetes mellitus * Liver and/or kidney disease that precludes a high protein load * Collagen supplementation or regular intake of other dietary supplements in the last 6 months.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in countermovement jump height (CMJ) | Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours) | Measured by force plate |
| Change in subjective pain score | Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours) | Measured by visual analogue scale |
| Change in maximal voluntary contraction (MVC) | Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours) | Measured by isokinetic dynamometer |
| Change in rate of force development (RFD) | Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours) | Measured by isokinetic dynamometer |
| Change in Achilles tendon cross-sectional area | Baseline and after 12 weeks | Measured by ultrasound |
| Change in Vastus Lateralis fibre length | Baseline (pre, post, 24 hours, 48 hours) and after 12 weeks (pre, post, 24 hours, 48 hours) | Measured by ultrasound |
| Change in collagen related blood markers | Baseline (pre, post, 2 hours, 24 hours, 48 hours) and after 12 weeks (pre, post, 2 hours, 24 hours, 48 hours) | Measured by blood analysis |
| Change in Achilles tendon echo intensity | Baseline and after 12 weeks | Measured by ultrasound |
| Change in Vastus Lateralis echo intensity | Baseline and after 12 weeks | Measured by ultrasound |
| Change in body composition parameters (fat mass, fat-free mass, extracellular mass, body cell mass) | Baseline and after 12 weeks | Measured by bioelectrical impedance analysis |
Countries
Austria
Outcome results
None listed