Patients With Axial SpA According to ASAS Criteria, Patients With Unilateral or Bilater Hip Damage According to BASRI Score, Age > 18
Conditions
Brief summary
Background: The hip joint is frequently affected in axial spondyloarthritis (SpA) of adults with destructive effects in untreated patients. About 35% of axial SpA patients had either unilateral or bilateral hip arthritis. Destruction is more common with early-onset, active disease, or enthesitis. Objectives: The aim of this study is to evaluate the effect of hip denervation (HD) and intra-articular hydration (IAH) on pain, function score, hip mobility scores in a cohort of axial SpA patients with grade 3 and 4 hip BASRI scores.
Interventions
DRUGhip denervation
Lidocaine 2% 2ml was injected into each genicular nerve
DRUGintra-articular hydration
10 ml; of normal; saline were injected inside the hip joint
DRUGCombined group
hip denervation and intra-articular hydration were conducted together
DRUGControl group
Normal; saline was injected subcutaneously
Sponsors
Suez Canal University
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age 18 or more * Axial; SpA fulfilled ASA criteria * BASRI score grade 3 or 4 for one hip at least
Exclusion criteria
* patients younger than 18 * Axial; SpA with normal hip or hip involvement less than 3 on BASRI score
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Harris functional hip score | Baseline, after 4 weeks and after 12 weeks | Pain receives 44 points, function 47 points, range of motion 5 points, and deformity 4 points. Function is subdivided into activities of daily living (14 points) and gait (33 points). The higher the HHS, the less dysfunction. A total score of \<70 is considered a poor result; 70-80 is considered fair, 80-90 is good, and 90-100 is an excellent result |
| Change in visual analogue scale | Baseline , after 4 weeks and after 12 weeks | 0 means no pain, 100 means the highest degree of pain |
| Change in range of motion of the hip | Baseline, after 4 weeks and after 12 weeks | hip flexion, extension , internal; rotation , external; rotation , abduction , and adduction all were recopreded |
| Change in semiquantitative tenderness score | Baseline, after 4 weeks and after 12 weeks | a score from 0-3, 90 means no tenderness and 3 means maximum tenderness |
Countries
Egypt
Outcome results
None listed