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Comparison of Different Objective Nociceptive Measurement Methods During Surgery

Comparison of Different Objective Nociceptive Measurement Methods During General Anesthesia or Sedation Under Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05218551
Enrollment
50
Registered
2022-02-01
Start date
2022-01-02
Completion date
2024-11-15
Last updated
2026-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nociceptive Pain

Brief summary

Traditionally, hemodynamic response e.g. pulse and blood pressure are used to evaluate pain in humans who are anesthetized. These values, however, can be affected by factors other than pain response . In this observational study, different types of digital methods are used that can distinguish signs of pain. However, the study aim to collect data and correlate in between different methods to ensure its reliability.

Detailed description

In humans who undergoing anesthesia or only receiving sedation with the addition of painkillers medication under surgery. Nociceptive response usually treats on the basis of hemodynamic and/or respiratory changes. These are interpreted together with a number of other parameters. The anesthetist can't be totally sure if it is nociceptive response or to light anesthesia given. Today, there are new monitors included techniques for measuring pain (nociception), but these are not used routinely. By put sensors (adhesive patches) on the skin and connect to these new devices perhaps the anesthetist can be more sure what stimuli patient are responding from, pain or light anesthesia. These techniques measure muscle activity including sweat gland which have been shown in other research studies demonstrate a higher accuracy regarding the response to nociception. The parameters are presented on a monitor as a value, 0-10 or 0-100. This research study is an observational study and intends to observe values / figures that arise from two different types of commercial monitors and manufactures. After the anesthesia, these values will be compared and evaluated in resect as well to hemodynamic response and in between monitors. The two techniques have never before been studied simultaneously on the same human been (control).

Interventions

None listed

Sponsors

Göteborg University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients over 18 yrs old, * Patients who will be anesthetized or sedated under intervention surgery or surgery

Exclusion criteria

* Not speaking Swedish * Neuro cognitive diorders e.g. dementia or can't respond on information given. * Chronic pain * Acute brain trauma * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
An index will be observed 0-100 and hemodynamic response, heart rate and blood pressure.numbers will be collected every minute during the surgery often 1 hourData collect only numbers. These are going to be correlated.

Countries

Sweden

Contacts

STUDY_DIRECTORPether Jildenstål, PhD

Göteborg University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 11, 2026