Neurological Injury, Out-Of-Hospital Cardiac Arrest
Conditions
Brief summary
To investigate the pharmacodynamics of light chain of NFL in patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.
Detailed description
To investigate the serum levels of the light chain of NFL at different time points after ICU admission (12, 24, 30, 36, 42, 48 hours after ICU admission) patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.
Interventions
None listed
Sponsors
University Medical Centre Maribor
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* out-of-hospital cardiac arrest successfully resuscitated and admitted to the ICU
Exclusion criteria
* trauma, drowning, electrocution, less than 18 years of age,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The difference in the dynamics of serum NFL levels measurements in patients with favorable neurological outcome compared to patients with non-favorable neurological outcome | 3 years | NFL levels |
Countries
Slovenia
Contacts
Primary ContactMatej Strnad, MD, PhD
Outcome results
None listed