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Availability and Advice on Test Uptake During the COVID-19 Pandemic: a Vignette Study.

Availability and Advice on Test Uptake During the COVID-19 Pandemic: a Vignette Study on Lateral Flow Testing Policy in the Netherlands.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05215483
Enrollment
3270
Registered
2022-01-31
Start date
2021-11-11
Completion date
2021-11-16
Last updated
2022-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Keywords

Test intentions, Lateral Flow test uptake

Brief summary

Lateral Flow Testing (LFT) use for COVID-19 related symptoms continues to rise, despite governmental advice to test at a test facility. In this study we investigate whether 1) adjusting the governmental testing advice will lead to a collective increase of people who test with COVID-19 symptoms and if this leads to a higher strategy sensitivity.

Detailed description

In an online randomised multi-factorial survey (vignette study) participants are randomised to assess four scenario's. Between subject testing advise is randomised (IV1; 2 levels) and the availability of LFT (IV2; 2 levels). Within subject we asked participants to assess their most likely behaviour on day 1 of symptoms and day 3 of unchanged symptoms (IV3; 2 levels). Corona-related symptoms are randomly presented (IV4; 4 levels) and new incidences of symptoms are presented in additional vignettes describing new months (IV5; 4 levels). Subjects are asked to immerse themselves in the scenario's before answering what their most likely behaviour would be: a) go to a test facility b) use a LFT c) wait and see or 4) no test. Participants who didn't choose the test facility on day 1 were presented with the same vignette on day 3 with unchanged symptoms, and were asked their most likely behaviour again. After assessing the scenario's, participants fill in a questionnaire assessing demographics, behavioural determinants related to test behaviour, vaccine status, current symptoms and previous experience with Corona and testing. The primary outcomes is defined as the average strategy sensitivity over time and therefore the chance of detecting a Covid-infection. Average strategy sensitivity is calculated by converting the choice of testing behaviour into the corresponding sensitivity score (PCR =1, LFT day 1 = .8, LFT day 3 = .7, wait and see and no test = 0), averaged over four scenario's. Our primary hypothesis is: 1. Adjusting the governmental testing advice will lead to a higher strategy sensitivity. In follow-up analysis we will explore the following hypothesis: 2. Availability of LFT at home will lead to a higher strategy sensitivity. 3. The type of corona related symptoms (mild or severe) are predictive of the type of test used. 4. When confronted with a new incidence of corona-related symptoms over time, strategy sensitivity will decline.

Interventions

BEHAVIORALCustomised testing advice

Customised advice: With Corona related symptoms, get tested at a test facility. If this isn't possible, use a Lateral Flow test.

BEHAVIORALRegular testing advice

Government guideline testing advice: With Corona related symptoms, get tested at a test facility.

BEHAVIORALLFT available

LFT availability: Enough lateral flow tests available at home

BEHAVIORALNo LFT available

LFT availability: No lateral flow tests available at home

Sponsors

National Institute for Public Health and the Environment (RIVM)
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Intervention model description

In an online randomised multi-factorial survey (vignette study) participants are randomised to assess four scenario's. Between subject testing advise is randomised (IV1; 2 levels) and the availability of LFT (IV2; 2 levels). Within subject we asked participants to assess their most likely behaviour on day 1 of symptoms and day 3 of unchanged symptoms (IV3; 2 levels). Corona-related symptoms are randomly presented (IV4; 4 levels) and new incidences of symptoms are presented in additional vignettes describing new months (IV5; 4 levels).

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Participants were recruited from an online research panel representative for the Dutch population. Inclusion Criteria: * non

Exclusion criteria

* non

Design outcomes

Primary

MeasureTime frameDescription
Average strategy sensitivity over time: day 1average strategy sensitivity day 1The sensitivity of the test chosen was used to convert each answer: test facility on day 1 = 1, LFT on day 1= 0.8, Wait and see or No test = 0. Sensitivity scores were then averaged over the four scenario's.
Maximum average strategy sensitivity over timemaximum average strategy sensitivity day 1 and 3The sensitivity of the test chosen was used to convert each answer: test facility on day 1 or day 3 = 1, LFT on day 1= 0.8, LFT on day 3= 0.7, Wait and see or No test = 0. Sensitivity scores were then averaged over the four scenario's. The highest score of day 1 and day 3 was used to calculate the maximum sensitivity score.

Secondary

MeasureTime frameDescription
Willingness to test day 1Day 1Willingness to test on day 1 (LFT & PCR =1, no test = 0), averaged over the four scenario's.
Willingness to test - maximumDay 1 and 3Willingness to test on day 1 and 3 (LFT & PCR =1, no test = 0), averaged over the four scenario's.
Type of test chosen day 1Day 1Percentage of testing behaviour (test facility, LFT, Wait and see, No test) on day 1, averaged over the four scenario's.
Type of test chosen day 3Day 3Percentage of testing behaviour (test facility, LFT, Wait and see, No test) on day 3, averaged over the four scenario's.

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026